HCSGD entry for CYSLTR1

1. General information

Official gene symbolCYSLTR1
Entrez ID10800
Gene full namecysteinyl leukotriene receptor 1
Other gene symbolsCYSLT1 CYSLT1R CYSLTR HG55 HMTMF81
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004974Leukotriene receptor activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0006816Calcium ion transportIEAbiological_process
GO:0006935ChemotaxisIEAbiological_process
GO:0006952Defense responseTASbiological_process
GO:0006954Inflammatory responseIEAbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationTASbiological_process
GO:0007585Respiratory gaseous exchangeTASbiological_process
GO:0016020MembraneTAScellular_component
GO:0045766Positive regulation of angiogenesisIEAbiological_process
GO:0045907Positive regulation of vasoconstrictionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.72646589420.69008388360.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0234595303
GSE13712_SHEARDown-0.0384105317
GSE13712_STATICDown-0.1152150215
GSE19018Up0.1497635114
GSE19899_A1Up0.1116956293
GSE19899_A2Down-0.0215192436
PubMed_21979375_A1Down-0.0417544132
PubMed_21979375_A2Down-0.0771513227
GSE35957Up0.1363277693
GSE36640Up0.3580983324
GSE54402Up0.0205233292
GSE9593Up0.0784331513
GSE43922Up0.0230953736
GSE24585Down-0.0209778557
GSE37065Up0.0827634642
GSE28863_A1Down-0.3075837083
GSE28863_A2Down-0.0744518566
GSE28863_A3Up0.1758973251
GSE28863_A4Down-0.0525922739
GSE48662Up0.0009837481

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

ZafirlukastDB00549 APRD00377
CinalukastDB00587 APRD00637
NedocromilDB00716 APRD01137
PranlukastDB01411 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017591MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.