HCSGD entry for ZNF268


1. General information

Official gene symbolZNF268
Entrez ID10795
Gene full namezinc finger protein 268
Other gene symbolsHZF3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0001934Positive regulation of protein phosphorylationIDAbiological_process
GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0003677DNA bindingNASmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005634NucleusIDA NAScellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEA NASbiological_process
GO:0007346Regulation of mitotic cell cycleIMPbiological_process
GO:0008284Positive regulation of cell proliferationIMPbiological_process
GO:0008285Negative regulation of cell proliferationIMPbiological_process
GO:0008588Release of cytoplasmic sequestered NF-kappaBIDAbiological_process
GO:0030154Cell differentiationIEAbiological_process
GO:0030335Positive regulation of cell migrationIMPbiological_process
GO:0043066Negative regulation of apoptotic processIMPbiological_process
GO:0043497Regulation of protein heterodimerization activityIDAbiological_process
GO:0045597Positive regulation of cell differentiationIMPbiological_process
GO:0045732Positive regulation of protein catabolic processIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0046022Positive regulation of transcription from RNA polymerase II promoter during mitosisIMPbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0071157Negative regulation of cell cycle arrestIMPbiological_process
GO:0071356Cellular response to tumor necrosis factorIDAbiological_process
GO:0090073Positive regulation of protein homodimerization activityIDAbiological_process
GO:1900119Positive regulation of execution phase of apoptosisIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.96675059840.13080306600.99999024730.6960912859

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0033575021
GSE13712_SHEARUp0.0675818887
GSE13712_STATICDown-0.0158278310
GSE19018Down-0.3338715676
GSE19899_A1Down-0.1754241928
GSE19899_A2Down-0.3351464734
PubMed_21979375_A1Up0.4021567348
PubMed_21979375_A2Down-0.1177107188
GSE35957Up0.0578609525
GSE36640Down-0.2674772893
GSE54402Down-0.2012126536
GSE9593Down-0.2459858748
GSE43922Down-0.0819033578
GSE24585Up0.1459535119
GSE37065Down-0.0746386217
GSE28863_A1Down-0.0633207231
GSE28863_A2Down-0.0402180727
GSE28863_A3Down-0.5668439759
GSE28863_A4Down-0.0549901279
GSE48662Down-0.0479742724

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.