HCSGD entry for ZNF274


1. General information

Official gene symbolZNF274
Entrez ID10782
Gene full namezinc finger protein 274
Other gene symbolsHFB101 ZF2 ZKSCAN19 ZSCAN51
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0003714Transcription corepressor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005813CentrosomeIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEA TASbiological_process
GO:0043565Sequence-specific DNA bindingIDAmolecular_function
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02547563920.97674793130.37463463691.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1477297175
GSE13712_SHEARUp1.2154580707
GSE13712_STATICUp0.6726338600
GSE19018Up0.0306606689
GSE19899_A1Up0.2264149545
GSE19899_A2Up0.5721616180
PubMed_21979375_A1Up0.8956369301
PubMed_21979375_A2Up0.9658263380
GSE35957Up0.1232145520
GSE36640Up0.1115266785
GSE54402Up0.1203704700
GSE9593Up0.0652927185
GSE43922Up0.3676052232
GSE24585Up0.0569139731
GSE37065Up0.2797111282
GSE28863_A1Up0.0007589651
GSE28863_A2Down-0.0502594580
GSE28863_A3Down-0.1391875576
GSE28863_A4Up0.0368586011
GSE48662Down-0.1587071720

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.