HCSGD entry for POP4


1. General information

Official gene symbolPOP4
Entrez ID10775
Gene full nameprocessing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
Other gene symbolsRPP29
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000172Ribonuclease MRP complexIEAcellular_component
GO:0003723RNA bindingIEAmolecular_function
GO:0004526Ribonuclease P activityIEAmolecular_function
GO:0004540Ribonuclease activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005655Nucleolar ribonuclease P complexIEAcellular_component
GO:0006364RRNA processingIEAbiological_process
GO:0006379MRNA cleavageIEAbiological_process
GO:0008033TRNA processingIEAbiological_process
GO:0030677Ribonuclease P complexIEAcellular_component
GO:0090501RNA phosphodiester bond hydrolysisTASbiological_process
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolyticTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.25371830480.85628755750.94350374401.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3743569286
GSE13712_SHEARUp0.0547936949
GSE13712_STATICUp0.1145320130
GSE19018Down-0.2114039098
GSE19899_A1Down-0.1220361354
GSE19899_A2Down-0.1073223192
PubMed_21979375_A1Up0.4378898468
PubMed_21979375_A2Up0.4321857317
GSE35957Down-0.0465048790
GSE36640Up0.0372873166
GSE54402Up0.0338866173
GSE9593Up0.0059677601
GSE43922Up0.0360068443
GSE24585Down-0.3754386594
GSE37065Up0.2062270531
GSE28863_A1Up0.1464818616
GSE28863_A2Up0.0563941706
GSE28863_A3Up0.3671153438
GSE28863_A4Up0.1657598384
GSE48662Down-0.1132715072

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029286MicroarrayFunctional MTI (Weak)19088304
hsa-miR-128-3pMIMAT0000424MIRT045865CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049425CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.