HCSGD entry for GIPC1

1. General information

Official gene symbolGIPC1
Entrez ID10755
Gene full nameGIPC PDZ domain containing family, member 1
Other gene symbolsC19orf3 GIPC GLUT1CBP Hs.6454 IIP-1 NIP RGS19IP1 SEMCAP SYNECTIIN SYNECTIN TIP-2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003779Actin bindingIEA ISSmolecular_function
GO:0005102Receptor bindingIPImolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmISScellular_component
GO:0005829CytosolIEA ISScellular_component
GO:0005903Brush borderIEAcellular_component
GO:0005938Cell cortexIDAcellular_component
GO:0006605Protein targetingIEA ISSbiological_process
GO:0007186G-protein coupled receptor signaling pathwayNASbiological_process
GO:0007268Synaptic transmissionIEA ISSbiological_process
GO:0008021Synaptic vesicleIEA ISScellular_component
GO:0012506Vesicle membraneIEA ISScellular_component
GO:0014047Glutamate secretionIEA ISSbiological_process
GO:0016020MembraneISScellular_component
GO:0016023Cytoplasmic membrane-bounded vesicleIDAcellular_component
GO:0017022Myosin bindingIEA ISSmolecular_function
GO:0030139Endocytic vesicleIEAcellular_component
GO:0030165PDZ domain bindingIEAmolecular_function
GO:0030511Positive regulation of transforming growth factor beta receptor signaling pathwayIEA ISSbiological_process
GO:0031647Regulation of protein stabilityIEA ISSbiological_process
GO:0032435Negative regulation of proteasomal ubiquitin-dependent protein catabolic processIEA ISSbiological_process
GO:0042803Protein homodimerization activityIEA ISSmolecular_function
GO:0043197Dendritic spineIEA ISScellular_component
GO:0043198Dendritic shaftIEA ISScellular_component
GO:0043542Endothelial cell migrationIEA ISSbiological_process
GO:0048167Regulation of synaptic plasticityIEA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15487826450.39411113180.78229721741.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1030412837
GSE13712_SHEARUp0.0343131670
GSE13712_STATICUp0.0377973578
GSE19018Up0.1206204561
GSE19899_A1Up0.0452500396
GSE19899_A2Up0.5585642661
PubMed_21979375_A1Up0.5570245140
PubMed_21979375_A2Up0.8413955528
GSE35957Down-0.2344031795
GSE36640Up0.6766579737
GSE54402Up0.3449272124
GSE9593Up0.1718159431
GSE43922Up0.0559021146
GSE24585Down-0.5002176902
GSE37065Down-0.2626787057
GSE28863_A1Down-0.2296411639
GSE28863_A2Down-0.4074515861
GSE28863_A3Down-0.4660123905
GSE28863_A4Up0.1088639001
GSE48662Down-0.0029238407

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-18a-3pMIMAT0002891MIRT040897CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.