HCSGD entry for MASP2
1. General information
| Official gene symbol | MASP2 |
|---|---|
| Entrez ID | 10747 |
| Gene full name | mannan-binding lectin serine peptidase 2 |
| Other gene symbols | MAP19 MASP-2 MASP1P1 sMAP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001867 | Complement activation, lectin pathway | IDA TAS | biological_process |
| GO:0004252 | Serine-type endopeptidase activity | IDA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0006956 | Complement activation | TAS | biological_process |
| GO:0006958 | Complement activation, classical pathway | IEA | biological_process |
| GO:0008233 | Peptidase activity | IDA | molecular_function |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0048306 | Calcium-dependent protein binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9220330421 | 0.6915114927 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0777813996 |
| GSE13712_SHEAR | Down | -0.0232626078 |
| GSE13712_STATIC | Up | 0.0491376902 |
| GSE19018 | Down | -0.0465012011 |
| GSE19899_A1 | Down | -0.0047145344 |
| GSE19899_A2 | Down | -0.0262341820 |
| PubMed_21979375_A1 | Down | -0.1075979982 |
| PubMed_21979375_A2 | Down | -0.0780303002 |
| GSE35957 | Up | 0.1765419684 |
| GSE36640 | Up | 0.0833289746 |
| GSE54402 | Down | -0.0063693602 |
| GSE9593 | Up | 0.0715093206 |
| GSE43922 | Up | 0.0793274577 |
| GSE24585 | Down | -0.0245393979 |
| GSE37065 | Down | -0.0704188258 |
| GSE28863_A1 | Down | -0.0748965739 |
| GSE28863_A2 | Down | -0.1252299328 |
| GSE28863_A3 | Up | 0.0604736713 |
| GSE28863_A4 | Down | -0.0874706027 |
| GSE48662 | Up | 0.0935234490 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Beta-Hydroxyasparagine | DB04527 | EXPT00462 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
