HCSGD entry for PTGES3

1. General information

Official gene symbolPTGES3
Entrez ID10728
Gene full nameprostaglandin E synthase 3 (cytosolic)
Other gene symbolsP23 TEBP cPGES
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000723Telomere maintenanceTASbiological_process
GO:0000781Chromosome, telomeric regionICcellular_component
GO:0001516Prostaglandin biosynthetic processIDAbiological_process
GO:0003720Telomerase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005697Telomerase holoenzyme complexIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006278RNA-dependent DNA replicationIDAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0019369Arachidonic acid metabolic processTASbiological_process
GO:0019371Cyclooxygenase pathwayTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0050220Prostaglandin-E synthase activityIDAmolecular_function
GO:0051082Unfolded protein bindingIDAmolecular_function
GO:0070389Chaperone cofactor-dependent protein refoldingIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.95798068460.13179781920.99999024730.6995463602

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0347691323
GSE13712_SHEARUp0.1774997256
GSE13712_STATICUp0.1273235032
GSE19018Up0.0293066264
GSE19899_A1Up0.0673220846
GSE19899_A2Down-0.1727631775
PubMed_21979375_A1Up0.1786261168
PubMed_21979375_A2Down-0.1383458295
GSE35957Down-0.4138163399
GSE36640Down-0.6295464904
GSE54402Up0.0666672421
GSE9593Down-0.3844616849
GSE43922Up0.1030319439
GSE24585Down-0.2565336103
GSE37065Down-0.0567170431
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.8029267790

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Grn163lDB05036 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-744-5pMIMAT0004945MIRT037524CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.