HCSGD entry for MGEA5

1. General information

Official gene symbolMGEA5
Entrez ID10724
Gene full namemeningioma expressed antigen 5 (hyaluronidase)
Other gene symbolsMEA5 NCOAT OGA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004402Histone acetyltransferase activityIEAmolecular_function
GO:0004415Hyalurononglucosaminidase activityTASmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0006044N-acetylglucosamine metabolic processIEAbiological_process
GO:0006516Glycoprotein catabolic processTASbiological_process
GO:0006612Protein targeting to membraneIEAbiological_process
GO:0007568AgingIEAbiological_process
GO:0010524Positive regulation of calcium ion transport into cytosolIEAbiological_process
GO:0010616Negative regulation of cardiac muscle adaptationIEAbiological_process
GO:0031343Positive regulation of cell killingIEAbiological_process
GO:0032024Positive regulation of insulin secretionIEAbiological_process
GO:0043243Positive regulation of protein complex disassemblyIEAbiological_process
GO:0045862Positive regulation of proteolysisIEAbiological_process
GO:0046060DATP metabolic processIEAbiological_process
GO:0046326Positive regulation of glucose importIEAbiological_process
GO:0048545Response to steroid hormoneIEAbiological_process
GO:0051054Positive regulation of DNA metabolic processIEAbiological_process
GO:0051901Positive regulation of mitochondrial depolarizationIEAbiological_process
GO:0060051Negative regulation of protein glycosylationIEAbiological_process
GO:0060124Positive regulation of growth hormone secretionIEAbiological_process
GO:0070265Necrotic cell deathIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.19824148400.48946730750.86041345201.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1323028093
GSE13712_SHEARUp0.6368036001
GSE13712_STATICUp0.1946935706
GSE19018Up0.3961226741
GSE19899_A1Down-0.0829363675
GSE19899_A2Down-0.0973551648
PubMed_21979375_A1Down-0.9183716423
PubMed_21979375_A2Up0.2149061911
GSE35957Down-0.2348263595
GSE36640Up0.2620137387
GSE54402Up0.0352577863
GSE9593Down-0.2098592504
GSE43922Down-0.2622380653
GSE24585Up0.4372619127
GSE37065Up0.0096603072
GSE28863_A1Up0.5135017351
GSE28863_A2Up0.2490743928
GSE28863_A3Down-0.3616934450
GSE28863_A4Up0.1569889870
GSE48662Down-0.2719541431

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-98-5pMIMAT0000096MIRT027558MicroarrayFunctional MTI (Weak)19088304
hsa-miR-30c-5pMIMAT0000244MIRT047872CLASHFunctional MTI (Weak)23622248
hsa-miR-17-5pMIMAT0000070MIRT050852CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.