HCSGD entry for SLC12A7

1. General information

Official gene symbolSLC12A7
Entrez ID10723
Gene full namesolute carrier family 12 (potassium/chloride transporters), member 7
Other gene symbolsKCC4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006810TransportTASbiological_process
GO:0006811Ion transportTASbiological_process
GO:0006813Potassium ion transportIEAbiological_process
GO:0006820Anion transportTASbiological_process
GO:0006821Chloride transportTASbiological_process
GO:0006884Cell volume homeostasisIEAbiological_process
GO:0015379Potassium:chloride symporter activityIEAmolecular_function
GO:0015698Inorganic anion transportTASbiological_process
GO:0034220Ion transmembrane transportTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:1902476Chloride transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.22620699440.38882579310.90789788051.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1472675834
GSE13712_SHEARDown-0.0424273003
GSE13712_STATICUp0.0266639972
GSE19018Up0.0425053097
GSE19899_A1Down-0.3317395460
GSE19899_A2Up0.4885196784
PubMed_21979375_A1Down-0.1431206638
PubMed_21979375_A2Up0.1704283915
GSE35957Down-0.8903978893
GSE36640Down-0.8131505958
GSE54402Down-0.1868666132
GSE9593Up0.1135175051
GSE43922Up0.0438407667
GSE24585Up0.1407382747
GSE37065Up0.2653060008
GSE28863_A1Up0.0229538081
GSE28863_A2Up0.3465194081
GSE28863_A3Up0.2379267760
GSE28863_A4Up0.0535802560
GSE48662Up0.2857592612

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Potassium ChlorideDB00761 APRD01322

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT016871MicroarrayFunctional MTI (Weak)18185580
hsa-miR-148b-3pMIMAT0000759MIRT019302MicroarrayFunctional MTI (Weak)17612493
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.