HCSGD entry for NRG3

1. General information

Official gene symbolNRG3
Entrez ID10718
Gene full nameneuregulin 3
Other gene symbolsHRG3 pro-NRG3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001558Regulation of cell growthNASbiological_process
GO:0005102Receptor bindingIEAmolecular_function
GO:0005576Extracellular regionNAScellular_component
GO:0005887Integral component of plasma membraneNAScellular_component
GO:0007171Activation of transmembrane receptor protein tyrosine kinase activityNASbiological_process
GO:0007389Pattern specification processIEAbiological_process
GO:0008083Growth factor activityNASmolecular_function
GO:0009790Embryo developmentIEAbiological_process
GO:0010469Regulation of receptor activityNASbiological_process
GO:0030297Transmembrane receptor protein tyrosine kinase activator activityNASmolecular_function
GO:0030971Receptor tyrosine kinase bindingNASmolecular_function
GO:0042325Regulation of phosphorylationNASbiological_process
GO:0042327Positive regulation of phosphorylationNASbiological_process
GO:0043085Positive regulation of catalytic activityNASbiological_process
GO:0045859Regulation of protein kinase activityNASbiological_process
GO:0045860Positive regulation of protein kinase activityNASbiological_process
GO:0050790Regulation of catalytic activityNASbiological_process
GO:0060596Mammary placode formationIEAbiological_process
GO:0061098Positive regulation of protein tyrosine kinase activityNASbiological_process
GO:2000273Positive regulation of receptor activityNASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.89200788340.06868693060.99999024730.4947239398

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2161457999
GSE13712_SHEARDown-4.0463625696
GSE13712_STATICDown-1.7133435155
GSE19018Up0.0008694512
GSE19899_A1Up0.1846569879
GSE19899_A2Up0.0292295689
PubMed_21979375_A1Down-0.0321571902
PubMed_21979375_A2Up0.0012701848
GSE35957Up0.1477015840
GSE36640Up0.1533943096
GSE54402Up0.1241577245
GSE9593Up0.0612828237
GSE43922Up0.0118275794
GSE24585Down-0.1963112834
GSE37065Down-0.0445032442
GSE28863_A1Down-0.0974967281
GSE28863_A2Down-0.0227283594
GSE28863_A3Up0.1595263345
GSE28863_A4Down-0.0537833648
GSE48662Up0.0265904465

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.