HCSGD entry for TBR1


1. General information

Official gene symbolTBR1
Entrez ID10716
Gene full nameT-box, brain, 1
Other gene symbolsTBR-1 TES-56
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000979RNA polymerase II core promoter sequence-specific DNA bindingIEAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007411Axon guidanceIEAbiological_process
GO:0007420Brain developmentTASbiological_process
GO:0010092Specification of organ identityIEAbiological_process
GO:0010975Regulation of neuron projection developmentIEAbiological_process
GO:0030902Hindbrain developmentIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.69580262910.81658250830.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0676574324
GSE13712_SHEARUp0.0025834960
GSE13712_STATICDown-0.1712364837
GSE19018Up0.0733228963
GSE19899_A1Up0.1522496595
GSE19899_A2Up0.0708105248
PubMed_21979375_A1Up0.0693558014
PubMed_21979375_A2Up0.0286718972
GSE35957Up0.1202957450
GSE36640Up0.0958453184
GSE54402Down-0.1891227199
GSE9593Up0.0255647131
GSE43922Up0.0210384722
GSE24585Up0.2097657874
GSE37065Down-0.1121806350
GSE28863_A1Down-0.0577822663
GSE28863_A2Down-0.1210069231
GSE28863_A3Up0.2552168551
GSE28863_A4Up0.0185629498
GSE48662Down-0.0099213821

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.