HCSGD entry for POLD3


1. General information

Official gene symbolPOLD3
Entrez ID10714
Gene full namepolymerase (DNA-directed), delta 3, accessory subunit
Other gene symbolsP66 P68
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000278Mitotic cell cycleTASbiological_process
GO:0000722Telomere maintenance via recombinationTASbiological_process
GO:0000723Telomere maintenanceTASbiological_process
GO:0000731DNA synthesis involved in DNA repairNASbiological_process
GO:0003887DNA-directed DNA polymerase activityNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0006260DNA replicationIEAbiological_process
GO:0006261DNA-dependent DNA replicationIEAbiological_process
GO:0006271DNA strand elongation involved in DNA replicationTASbiological_process
GO:0006281DNA repairTASbiological_process
GO:0006283Transcription-coupled nucleotide-excision repairTASbiological_process
GO:0006284Base-excision repairTASbiological_process
GO:0006289Nucleotide-excision repairTASbiological_process
GO:0006297Nucleotide-excision repair, DNA gap fillingIMP TASbiological_process
GO:0006298Mismatch repairNASbiological_process
GO:0032201Telomere maintenance via semi-conservative replicationTASbiological_process
GO:0043625Delta DNA polymerase complexNAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97141689150.00818450670.99999024730.1805736798

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1560167237
GSE13712_SHEARDown-0.4837702515
GSE13712_STATICUp0.0336786373
GSE19018Up0.1437953845
GSE19899_A1Down-0.3186883879
GSE19899_A2Down-1.3394910661
PubMed_21979375_A1Down-0.4358061596
PubMed_21979375_A2Down-1.1054084070
GSE35957Down-0.7501539598
GSE36640Down-2.1925620991
GSE54402Down-0.3280202577
GSE9593Down-0.4128896291
GSE43922Down-0.6331915681
GSE24585Up0.2526215192
GSE37065Down-0.0230353887
GSE28863_A1Up0.1640765186
GSE28863_A2Up0.3122515545
GSE28863_A3Down-0.1071910591
GSE28863_A4Up0.1416959726
GSE48662Down-0.7276539906

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-103a-3pMIMAT0000101MIRT027117SequencingFunctional MTI (Weak)20371350
hsa-miR-744-5pMIMAT0004945MIRT037579CLASHFunctional MTI (Weak)23622248
hsa-miR-130b-5pMIMAT0004680MIRT038291CLASHFunctional MTI (Weak)23622248
hsa-miR-186-5pMIMAT0000456MIRT045077CLASHFunctional MTI (Weak)23622248
hsa-miR-149-5pMIMAT0000450MIRT045481CLASHFunctional MTI (Weak)23622248
hsa-miR-29a-3pMIMAT0000086MIRT049970CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.