HCSGD entry for CCT8
1. General information
| Official gene symbol | CCT8 |
|---|---|
| Entrez ID | 10694 |
| Gene full name | chaperonin containing TCP1, subunit 8 (theta) |
| Other gene symbols | C21orf112 Cctq D21S246 PRED71 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002199 | Zona pellucida receptor complex | IEA | cellular_component |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA TAS | cellular_component |
| GO:0005832 | Chaperonin-containing T-complex | IEA | cellular_component |
| GO:0005874 | Microtubule | IDA | cellular_component |
| GO:0006200 | ATP catabolic process | TAS | biological_process |
| GO:0006457 | Protein folding | IEA TAS | biological_process |
| GO:0007339 | Binding of sperm to zona pellucida | IEA | biological_process |
| GO:0016235 | Aggresome | IDA | cellular_component |
| GO:0042623 | ATPase activity, coupled | TAS | molecular_function |
| GO:0044267 | Cellular protein metabolic process | IEA TAS | biological_process |
| GO:0044297 | Cell body | IEA | cellular_component |
| GO:0045111 | Intermediate filament cytoskeleton | IDA | cellular_component |
| GO:0051082 | Unfolded protein binding | IEA | molecular_function |
| GO:0051084 | 'de novo' posttranslational protein folding | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8998156263 | 0.3402196497 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0217717108 |
| GSE13712_SHEAR | Down | -0.0131718775 |
| GSE13712_STATIC | Down | -0.0806986611 |
| GSE19018 | Down | -0.0577858868 |
| GSE19899_A1 | Up | 0.1821731566 |
| GSE19899_A2 | Up | 0.1018119663 |
| PubMed_21979375_A1 | Up | 0.1820597944 |
| PubMed_21979375_A2 | Down | -0.0553518901 |
| GSE35957 | Down | -0.0710866970 |
| GSE36640 | Down | -0.4894661988 |
| GSE54402 | Up | 0.2673760692 |
| GSE9593 | Down | -0.2982143669 |
| GSE43922 | Up | 0.0933666247 |
| GSE24585 | Down | -0.2512691398 |
| GSE37065 | Down | -0.1147305324 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.3804413100 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT039814 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-301a-3p | MIMAT0000688 | MIRT044212 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048794 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051139 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
