HCSGD entry for TNFSF13B
1. General information
| Official gene symbol | TNFSF13B |
|---|---|
| Entrez ID | 10673 |
| Gene full name | tumor necrosis factor (ligand) superfamily, member 13b |
| Other gene symbols | BAFF BLYS CD257 DTL TALL-1 TALL1 THANK TNFSF20 ZTNF4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001782 | B cell homeostasis | IEA | biological_process |
| GO:0002636 | Positive regulation of germinal center formation | IEA | biological_process |
| GO:0005102 | Receptor binding | TAS | molecular_function |
| GO:0005125 | Cytokine activity | IEA | molecular_function |
| GO:0005164 | Tumor necrosis factor receptor binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006955 | Immune response | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | TAS | biological_process |
| GO:0016021 | Integral component of membrane | NAS | cellular_component |
| GO:0030890 | Positive regulation of B cell proliferation | IEA | biological_process |
| GO:0031295 | T cell costimulation | IEA | biological_process |
| GO:0031296 | B cell costimulation | IEA | biological_process |
| GO:0042102 | Positive regulation of T cell proliferation | IEA | biological_process |
| GO:0048305 | Immunoglobulin secretion | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0035270354 | 0.9264148589 | 0.1614523478 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6900388658 |
| GSE13712_SHEAR | Up | 0.0532776827 |
| GSE13712_STATIC | Up | 0.7355859381 |
| GSE19018 | Up | 0.2572272617 |
| GSE19899_A1 | Up | 0.0334845657 |
| GSE19899_A2 | Up | 0.5317458891 |
| PubMed_21979375_A1 | Up | 1.0504643910 |
| PubMed_21979375_A2 | Up | 0.5498509920 |
| GSE35957 | Down | -1.9124033128 |
| GSE36640 | Up | 1.4037736049 |
| GSE54402 | Up | 0.9426945784 |
| GSE9593 | Up | 0.6511162703 |
| GSE43922 | Up | 0.0264328522 |
| GSE24585 | Up | 0.0906856112 |
| GSE37065 | Up | 1.5071835990 |
| GSE28863_A1 | Up | 0.7638339651 |
| GSE28863_A2 | Down | -0.1270820966 |
| GSE28863_A3 | Down | -0.1097864487 |
| GSE28863_A4 | Up | 0.1112807585 |
| GSE48662 | Up | 0.1969460519 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 1,4-Diethylene Dioxide | DB03316 | EXPT01208 |
| Citric Acid | DB04272 | EXPT00922 |
| Belimumab | DB08879 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024564 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026689 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
