HCSGD entry for LBX1

1. General information

Official gene symbolLBX1
Entrez ID10660
Gene full nameladybird homeobox 1
Other gene symbolsHPX-6 HPX6 LBX1H homeobox
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000976Transcription regulatory region sequence-specific DNA bindingIEAmolecular_function
GO:0001947Heart loopingIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005667Transcription factor complexIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007517Muscle organ developmentIEAbiological_process
GO:0008285Negative regulation of cell proliferationIEAbiological_process
GO:0009653Anatomical structure morphogenesisTASbiological_process
GO:0021522Spinal cord motor neuron differentiationIEAbiological_process
GO:0021920Regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specificationIEAbiological_process
GO:0045665Negative regulation of neuron differentiationIEAbiological_process
GO:0048664Neuron fate determinationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.68035475100.75855394550.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0584134597
GSE13712_SHEARDown-0.0755361128
GSE13712_STATICDown-0.0094154137
GSE19018Up0.1211899975
GSE19899_A1Down-0.0456937970
GSE19899_A2Down-0.0593602362
PubMed_21979375_A1Down0.0000000000
PubMed_21979375_A2Down-0.1692099132
GSE35957Up0.0845819550
GSE36640Up0.0753788470
GSE54402Down-0.0437783315
GSE9593Up0.1846326501
GSE43922Up0.0578086551
GSE24585Down-0.0058579812
GSE37065Down-0.1846785353
GSE28863_A1Down-0.0427621964
GSE28863_A2Up0.0027183947
GSE28863_A3Up0.3798875614
GSE28863_A4Down-0.0242971066
GSE48662Up0.3288360586

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.