HCSGD entry for SPINT2
1. General information
| Official gene symbol | SPINT2 |
|---|---|
| Entrez ID | 10653 |
| Gene full name | serine peptidase inhibitor, Kunitz type, 2 |
| Other gene symbols | DIAR3 HAI-2 HAI2 Kop PB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004866 | Endopeptidase inhibitor activity | TAS | molecular_function |
| GO:0004867 | Serine-type endopeptidase inhibitor activity | IEA | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006928 | Cellular component movement | TAS | biological_process |
| GO:0010951 | Negative regulation of endopeptidase activity | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0052548 | Regulation of endopeptidase activity | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6496820941 | 0.0099570837 | 0.9999902473 | 0.1979459215 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2998290247 |
| GSE13712_SHEAR | Down | -0.9746194712 |
| GSE13712_STATIC | Down | -1.2717166207 |
| GSE19018 | Down | -0.1199419085 |
| GSE19899_A1 | Down | -0.1483996748 |
| GSE19899_A2 | Down | -0.3444132659 |
| PubMed_21979375_A1 | Down | -0.9424619596 |
| PubMed_21979375_A2 | Down | -0.4097427619 |
| GSE35957 | Down | -1.0091916361 |
| GSE36640 | Down | -0.3846384351 |
| GSE54402 | Down | -1.0307981084 |
| GSE9593 | Down | -0.1493356167 |
| GSE43922 | Up | 0.0294765636 |
| GSE24585 | Up | 0.9806348181 |
| GSE37065 | Up | 0.2217132101 |
| GSE28863_A1 | Down | -0.4708898504 |
| GSE28863_A2 | Down | -0.0097892372 |
| GSE28863_A3 | Up | 0.2896968451 |
| GSE28863_A4 | Up | 0.2201661837 |
| GSE48662 | Up | 0.6042598455 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
