HCSGD entry for IGF2BP2
1. General information
| Official gene symbol | IGF2BP2 |
|---|---|
| Entrez ID | 10644 |
| Gene full name | insulin-like growth factor 2 mRNA binding protein 2 |
| Other gene symbols | IMP-2 IMP2 VICKZ2 p62 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0003730 | MRNA 3'-UTR binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005856 | Cytoskeleton | IDA | cellular_component |
| GO:0009653 | Anatomical structure morphogenesis | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0017148 | Negative regulation of translation | ISS | biological_process |
| GO:0042035 | Regulation of cytokine biosynthetic process | IC | biological_process |
| GO:0045182 | Translation regulator activity | ISS | molecular_function |
| GO:0048027 | MRNA 5'-UTR binding | IDA | molecular_function |
| GO:0051028 | MRNA transport | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3853992515 | 0.2004377911 | 0.9999902473 | 0.8658662564 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3335770733 |
| GSE13712_SHEAR | Up | 0.4225530575 |
| GSE13712_STATIC | Up | 0.3463806731 |
| GSE19018 | Up | 0.1816128543 |
| GSE19899_A1 | Down | -0.1411608211 |
| GSE19899_A2 | Down | -0.0773120106 |
| PubMed_21979375_A1 | Up | 0.5559927848 |
| PubMed_21979375_A2 | Down | -0.2144400066 |
| GSE35957 | Up | 0.3864660800 |
| GSE36640 | Down | -0.5478803376 |
| GSE54402 | Down | -0.2744565530 |
| GSE9593 | Up | 0.0213409212 |
| GSE43922 | Down | -0.4427128472 |
| GSE24585 | Up | 0.0589537308 |
| GSE37065 | Down | -0.1424512270 |
| GSE28863_A1 | Up | 0.0446528820 |
| GSE28863_A2 | Up | 0.0441760585 |
| GSE28863_A3 | Up | 0.1269891652 |
| GSE28863_A4 | Down | -0.1521992815 |
| GSE48662 | Up | 0.3742567397 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-18a-5p | MIMAT0000072 | MIRT000792 | Microarray//Northern blot | Functional MTI (Weak) | 16331254 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT005241 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018969 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027853 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037361 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125a-3p | MIMAT0004602 | MIRT038642 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043535 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
