HCSGD entry for RGS14


1. General information

Official gene symbolRGS14
Entrez ID10636
Gene full nameregulator of G-protein signaling 14
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000922Spindle poleISScellular_component
GO:0001965G-protein alpha-subunit bindingIEAmolecular_function
GO:0005057Receptor signaling protein activityIEA ISSmolecular_function
GO:0005092GDP-dissociation inhibitor activityIDAmolecular_function
GO:0005096GTPase activator activityIBA IDAmolecular_function
GO:0005634NucleusIDA ISScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIBA ISScellular_component
GO:0005813CentrosomeISScellular_component
GO:0005819SpindleIDAcellular_component
GO:0005874MicrotubuleIEAcellular_component
GO:0005886Plasma membraneIBA ISScellular_component
GO:0006913Nucleocytoplasmic transportISSbiological_process
GO:0006979Response to oxidative stressISSbiological_process
GO:0007051Spindle organizationIMPbiological_process
GO:0007059Chromosome segregationISSbiological_process
GO:0007067MitosisIEAbiological_process
GO:0007612LearningISSbiological_process
GO:0007616Long-term memoryISSbiological_process
GO:0008017Microtubule bindingIDAmolecular_function
GO:0008277Regulation of G-protein coupled receptor protein signaling pathwayTASbiological_process
GO:0008542Visual learningISSbiological_process
GO:0010070Zygote asymmetric cell divisionISSbiological_process
GO:0014069Postsynaptic densityISScellular_component
GO:0016604Nuclear bodyISScellular_component
GO:0016605PML bodyIEAcellular_component
GO:0019901Protein kinase bindingIEAmolecular_function
GO:0030054Cell junctionIEAcellular_component
GO:0030159Receptor signaling complex scaffold activityISSmolecular_function
GO:0030425DendriteISScellular_component
GO:0030695GTPase regulator activityIEAmolecular_function
GO:0031914Negative regulation of synaptic plasticityISSbiological_process
GO:0032794GTPase activating protein bindingIEAmolecular_function
GO:0035556Intracellular signal transductionISSbiological_process
GO:0038032Termination of G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0043085Positive regulation of catalytic activityIBA IDA TASbiological_process
GO:0043197Dendritic spineISScellular_component
GO:0043407Negative regulation of MAP kinase activityISSbiological_process
GO:0043547Positive regulation of GTPase activityIBA IDA TASbiological_process
GO:0043620Regulation of DNA-templated transcription in response to stressISSbiological_process
GO:0045111Intermediate filament cytoskeletonIDAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0048008Platelet-derived growth factor receptor signaling pathwayISSbiological_process
GO:0050769Positive regulation of neurogenesisISSbiological_process
GO:0051301Cell divisionIMPbiological_process
GO:0060291Long-term synaptic potentiationISSbiological_process
GO:0070373Negative regulation of ERK1 and ERK2 cascadeISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82186042320.44937033930.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1087588918
GSE13712_SHEARDown-0.0296622299
GSE13712_STATICUp0.2093580292
GSE19018Up0.1205206886
GSE19899_A1Down-0.0256939283
GSE19899_A2Up0.0572121373
PubMed_21979375_A1Down-0.4544806848
PubMed_21979375_A2Down-0.1754676595
GSE35957Down-0.3541582898
GSE36640Up0.0727720315
GSE54402Down-0.0254746551
GSE9593Up0.1201454293
GSE43922Up0.1379491404
GSE24585Up0.0630848099
GSE37065Up0.0039569726
GSE28863_A1Down-0.2726530689
GSE28863_A2Down-0.0987611778
GSE28863_A3Up0.2216189635
GSE28863_A4Down-0.0026191665
GSE48662Up0.0292599994

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-128-3pMIMAT0000424MIRT021874MicroarrayFunctional MTI (Weak)17612493
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.