HCSGD entry for POLR3C

1. General information

Official gene symbolPOLR3C
Entrez ID10623
Gene full namepolymerase (RNA) III (DNA directed) polypeptide C (62kD)
Other gene symbolsRPC3 RPC62
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0003899DNA-directed RNA polymerase activityIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005666DNA-directed RNA polymerase III complexTAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006359Regulation of transcription from RNA polymerase III promoterTASbiological_process
GO:0006383Transcription from RNA polymerase III promoterTASbiological_process
GO:0006385Transcription elongation from RNA polymerase III promoterTASbiological_process
GO:0006386Termination of RNA polymerase III transcriptionTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0032481Positive regulation of type I interferon productionTASbiological_process
GO:0032728Positive regulation of interferon-beta productionIMPbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045089Positive regulation of innate immune responseIMPbiological_process
GO:0051607Defense response to virusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82548449150.08248255390.99999024730.5436135169

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2163557583
GSE13712_SHEARDown-0.0799970444
GSE13712_STATICUp0.1326580750
GSE19018Down-0.0756821437
GSE19899_A1Down-0.7609028518
GSE19899_A2Down-0.6475553049
PubMed_21979375_A1Down-0.9004259306
PubMed_21979375_A2Down-1.1448804176
GSE35957Up0.1054545701
GSE36640Up0.4438049628
GSE54402Up0.0877518995
GSE9593Up0.3172167259
GSE43922Down-0.6387287171
GSE24585Down-0.0240877107
GSE37065Down-0.0417882103
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.2900803143

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.