HCSGD entry for POLR3G
1. General information
| Official gene symbol | POLR3G |
|---|---|
| Entrez ID | 10622 |
| Gene full name | polymerase (RNA) III (DNA directed) polypeptide G (32kD) |
| Other gene symbols | RPC32 RPC7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003899 | DNA-directed RNA polymerase activity | IEA | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005666 | DNA-directed RNA polymerase III complex | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006359 | Regulation of transcription from RNA polymerase III promoter | TAS | biological_process |
| GO:0006383 | Transcription from RNA polymerase III promoter | TAS | biological_process |
| GO:0006385 | Transcription elongation from RNA polymerase III promoter | TAS | biological_process |
| GO:0006386 | Termination of RNA polymerase III transcription | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0032481 | Positive regulation of type I interferon production | TAS | biological_process |
| GO:0032728 | Positive regulation of interferon-beta production | IMP | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0045089 | Positive regulation of innate immune response | IMP | biological_process |
| GO:0051607 | Defense response to virus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0712657916 | 0.1380752593 | 0.5692304915 | 0.7156910004 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0473283793 |
| GSE13712_SHEAR | Up | 2.4885946478 |
| GSE13712_STATIC | Up | 2.4109020134 |
| GSE19018 | Up | 0.4310047136 |
| GSE19899_A1 | Up | 0.0488218919 |
| GSE19899_A2 | Down | -0.5844082938 |
| PubMed_21979375_A1 | Up | 0.6069050139 |
| PubMed_21979375_A2 | Down | -0.5528464016 |
| GSE35957 | Down | -0.0230511146 |
| GSE36640 | Down | -0.7430665550 |
| GSE54402 | Up | 0.1158308028 |
| GSE9593 | Down | -0.5786664063 |
| GSE43922 | Down | -0.2448187388 |
| GSE24585 | Down | -0.3077568326 |
| GSE37065 | Down | -0.2139856184 |
| GSE28863_A1 | Down | -0.0858848946 |
| GSE28863_A2 | Up | 0.2353256345 |
| GSE28863_A3 | Down | -0.1513674425 |
| GSE28863_A4 | Up | 0.1183049928 |
| GSE48662 | Down | -0.3260646543 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002588 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029218 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029218 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052000 | CLASH | Functional MTI (Weak) | 23622248 |
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