HCSGD entry for SPAG5
1. General information
| Official gene symbol | SPAG5 |
|---|---|
| Entrez ID | 10615 |
| Gene full name | sperm associated antigen 5 |
| Other gene symbols | DEEPEST MAP126 hMAP126 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000070 | Mitotic sister chromatid segregation | IMP | biological_process |
| GO:0000776 | Kinetochore | IDA | cellular_component |
| GO:0000777 | Condensed chromosome kinetochore | IEA | cellular_component |
| GO:0000922 | Spindle pole | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0007049 | Cell cycle | NAS | biological_process |
| GO:0007051 | Spindle organization | IMP NAS | biological_process |
| GO:0007059 | Chromosome segregation | IMP | biological_process |
| GO:0035371 | Microtubule plus-end | IDA | cellular_component |
| GO:0048015 | Phosphatidylinositol-mediated signaling | NAS | biological_process |
| GO:0051988 | Regulation of attachment of spindle microtubules to kinetochore | IMP | biological_process |
| GO:0072686 | Mitotic spindle | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9753547434 | 0.0000224232 | 0.9999902473 | 0.0085375000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.7190651799 |
| GSE13712_SHEAR | Down | -0.1636704718 |
| GSE13712_STATIC | Down | -1.2183122291 |
| GSE19018 | Up | 0.2153925333 |
| GSE19899_A1 | Down | -1.4320299046 |
| GSE19899_A2 | Down | -4.4133214954 |
| PubMed_21979375_A1 | Down | -2.3127955664 |
| PubMed_21979375_A2 | Down | -4.3057610972 |
| GSE35957 | Down | -2.8876910731 |
| GSE36640 | Down | -4.9896882985 |
| GSE54402 | Down | -1.0067028845 |
| GSE9593 | Down | -1.3903732297 |
| GSE43922 | Down | -1.9305282722 |
| GSE24585 | Up | 0.0777215399 |
| GSE37065 | Down | -0.6674260648 |
| GSE28863_A1 | Down | -0.0143241203 |
| GSE28863_A2 | Up | 0.4802456550 |
| GSE28863_A3 | Down | -0.4043693948 |
| GSE28863_A4 | Up | 0.1945656584 |
| GSE48662 | Down | -2.3091911833 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-877-3p | MIMAT0004950 | MIRT036921 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-769-5p | MIMAT0003886 | MIRT039188 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045449 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046943 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
