HCSGD entry for USP16

1. General information

Official gene symbolUSP16
Entrez ID10600
Gene full nameubiquitin specific peptidase 16
Other gene symbolsUBP-M
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003713Transcription coactivator activityIDAmolecular_function
GO:0004197Cysteine-type endopeptidase activityIMPmolecular_function
GO:0004221Ubiquitin thiolesterase activityIDA IEAmolecular_function
GO:0004843Ubiquitin-specific protease activityIDAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmTAScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterISSbiological_process
GO:0006511Ubiquitin-dependent protein catabolic processIEAbiological_process
GO:0006974Cellular response to DNA damage stimulusIDAbiological_process
GO:0007049Cell cycleTASbiological_process
GO:0007067MitosisIDAbiological_process
GO:0008270Zinc ion bindingIDA IEAmolecular_function
GO:0016578Histone deubiquitinationIDAbiological_process
GO:0035522Monoubiquitinated histone H2A deubiquitinationISSbiological_process
GO:0042393Histone bindingIDAmolecular_function
GO:0043130Ubiquitin bindingIDAmolecular_function
GO:0045893Positive regulation of transcription, DNA-templatedIMPbiological_process
GO:0045901Positive regulation of translational elongationIMPbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterISSbiological_process
GO:0051289Protein homotetramerizationIPIbiological_process
GO:0070537Histone H2A K63-linked deubiquitinationIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.50653410960.20965006650.99999024730.8847579926

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0741976864
GSE13712_SHEARUp0.3446730233
GSE13712_STATICUp0.0489198637
GSE19018Down-0.4405871136
GSE19899_A1Down-0.0081773648
GSE19899_A2Down-0.0869171408
PubMed_21979375_A1Up0.4041417346
PubMed_21979375_A2Up0.3943047605
GSE35957Up0.0020099269
GSE36640Down-0.3568155000
GSE54402Up0.2600046599
GSE9593Down-0.1515712720
GSE43922Down-0.0151910576
GSE24585Down-0.3677708045
GSE37065Up0.0316105393
GSE28863_A1Down-0.2306846972
GSE28863_A2Down-0.0461014543
GSE28863_A3Down-0.7742288312
GSE28863_A4Up0.3323458666
GSE48662Up0.0454023317

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-324-5pMIMAT0000761MIRT043256CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044492CLASHFunctional MTI (Weak)23622248
hsa-miR-182-5pMIMAT0000259MIRT047199CLASHFunctional MTI (Weak)23622248
hsa-miR-30a-5pMIMAT0000087MIRT049954CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.