HCSGD entry for CENPB
1. General information
| Official gene symbol | CENPB |
|---|---|
| Entrez ID | 1059 |
| Gene full name | centromere protein B, 80kDa |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000775 | Chromosome, centromeric region | IDA | cellular_component |
| GO:0003682 | Chromatin binding | NAS | molecular_function |
| GO:0003696 | Satellite DNA binding | NAS | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0019237 | Centromeric DNA binding | IC | molecular_function |
| GO:0043565 | Sequence-specific DNA binding | TAS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3048643479 | 0.3529241442 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1571004805 |
| GSE13712_SHEAR | Down | -0.2043242493 |
| GSE13712_STATIC | Down | -0.3445302624 |
| GSE19018 | Down | -0.2101105619 |
| GSE19899_A1 | Down | -0.0814892449 |
| GSE19899_A2 | Up | 1.0139176515 |
| PubMed_21979375_A1 | Down | -0.1702613414 |
| PubMed_21979375_A2 | Down | -0.0027048132 |
| GSE35957 | Up | 0.8817913085 |
| GSE36640 | Up | 0.0764466665 |
| GSE54402 | Up | 0.2084847699 |
| GSE9593 | Down | -0.0683634784 |
| GSE43922 | Up | 0.0512046360 |
| GSE24585 | Up | 0.0092590544 |
| GSE37065 | Down | -0.1120840370 |
| GSE28863_A1 | Down | -0.2946775888 |
| GSE28863_A2 | Down | -0.1501310255 |
| GSE28863_A3 | Up | 0.0777203798 |
| GSE28863_A4 | Up | 0.0987940952 |
| GSE48662 | Up | 0.1557027737 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT032351 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043157 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045539 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
