HCSGD entry for DRAP1
1. General information
| Official gene symbol | DRAP1 |
|---|---|
| Entrez ID | 10589 |
| Gene full name | DR1-associated protein 1 (negative cofactor 2 alpha) |
| Other gene symbols | NC2-alpha |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0003677 | DNA binding | TAS | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | TAS | molecular_function |
| GO:0003714 | Transcription corepressor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0008134 | Transcription factor binding | IEA | molecular_function |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0046982 | Protein heterodimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1030625470 | 0.3624364804 | 0.6679673148 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6955269544 |
| GSE13712_SHEAR | Up | 0.2910054479 |
| GSE13712_STATIC | Up | 0.2617784935 |
| GSE19018 | Up | 0.2065287352 |
| GSE19899_A1 | Up | 0.3117090585 |
| GSE19899_A2 | Up | 0.4648597656 |
| PubMed_21979375_A1 | Up | 0.4124353332 |
| PubMed_21979375_A2 | Down | -0.3559109253 |
| GSE35957 | Down | -0.6480500267 |
| GSE36640 | Down | -0.3809519490 |
| GSE54402 | Up | 0.1693099932 |
| GSE9593 | Down | -0.0645090769 |
| GSE43922 | Down | -0.0164937568 |
| GSE24585 | Down | -0.1977275178 |
| GSE37065 | Down | -0.1633964765 |
| GSE28863_A1 | Down | -0.1642356274 |
| GSE28863_A2 | Up | 0.0891684411 |
| GSE28863_A3 | Down | -0.1138298321 |
| GSE28863_A4 | Up | 0.6002602037 |
| GSE48662 | Down | -0.2632984712 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020517 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023515 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038135 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
