HCSGD entry for SORBS1

1. General information

Official gene symbolSORBS1
Entrez ID10580
Gene full namesorbin and SH3 domain containing 1
Other gene symbolsCAP FLAF2 R85FL SH3D5 SH3P12 SORB1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001725Stress fiberISScellular_component
GO:0003779Actin bindingTASmolecular_function
GO:0005070SH3/SH2 adaptor activityIC ISSmolecular_function
GO:0005158Insulin receptor bindingIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005813CentrosomeIDAcellular_component
GO:0005829CytosolISS TAScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005899Insulin receptor complexIDAcellular_component
GO:0005913Cell-cell adherens junctionISScellular_component
GO:0005915Zonula adherensTAScellular_component
GO:0005924Cell-substrate adherens junctionISScellular_component
GO:0005925Focal adhesionIDAcellular_component
GO:0006936Muscle contractionTASbiological_process
GO:0007015Actin filament organizationIEAbiological_process
GO:0007160Cell-matrix adhesionTASbiological_process
GO:0008092Cytoskeletal protein bindingTASmolecular_function
GO:0008286Insulin receptor signaling pathwayIEA ISSbiological_process
GO:0009967Positive regulation of signal transductionIC ISSbiological_process
GO:0015758Glucose transportISSbiological_process
GO:0016363Nuclear matrixIEAcellular_component
GO:0019901Protein kinase bindingIEAmolecular_function
GO:0032869Cellular response to insulin stimulusISSbiological_process
GO:0043149Stress fiber assemblyISSbiological_process
GO:0045121Membrane raftISScellular_component
GO:0045725Positive regulation of glycogen biosynthetic processISSbiological_process
GO:0046326Positive regulation of glucose importISSbiological_process
GO:0046889Positive regulation of lipid biosynthetic processISSbiological_process
GO:0048041Focal adhesion assemblyISSbiological_process
GO:0090004Positive regulation of establishment of protein localization to plasma membraneISSbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.67322843360.26696775960.99999024730.9890025176

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-1.0957663476
GSE13712_SHEARUp0.2825482169
GSE13712_STATICDown-0.0980039179
GSE19018Down-0.3229453694
GSE19899_A1Up0.1395916328
GSE19899_A2Up0.0672315632
PubMed_21979375_A1Up0.0473223793
PubMed_21979375_A2Up0.0975936398
GSE35957Up0.0124046722
GSE36640Up0.6891092886
GSE54402Down-0.0041148964
GSE9593Down-0.2852878586
GSE43922Up0.0212205803
GSE24585Down-0.3148260010
GSE37065Up0.2613506868
GSE28863_A1Down-0.0072801169
GSE28863_A2Down-0.0915796204
GSE28863_A3Up0.2265517235
GSE28863_A4Down-0.1376619809
GSE48662Down-0.0839041673

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-320aMIMAT0000510MIRT044804CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.