HCSGD entry for ARFGEF1
1. General information
Official gene symbol | ARFGEF1 |
---|---|
Entrez ID | 10565 |
Gene full name | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) |
Other gene symbols | ARFGEP1 BIG1 P200 |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network

This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0000139 | Golgi membrane | IDA | cellular_component |
GO:0005085 | Guanyl-nucleotide exchange factor activity | IDA | molecular_function |
GO:0005086 | ARF guanyl-nucleotide exchange factor activity | IBA IEA | molecular_function |
GO:0005515 | Protein binding | IPI | molecular_function |
GO:0005634 | Nucleus | IDA | cellular_component |
GO:0005730 | Nucleolus | IDA | cellular_component |
GO:0005737 | Cytoplasm | IDA | cellular_component |
GO:0005794 | Golgi apparatus | IDA | cellular_component |
GO:0005802 | Trans-Golgi network | IBA ISS | cellular_component |
GO:0005829 | Cytosol | IDA | cellular_component |
GO:0006887 | Exocytosis | TAS | biological_process |
GO:0007030 | Golgi organization | IMP | biological_process |
GO:0008060 | ARF GTPase activator activity | IDA | molecular_function |
GO:0010256 | Endomembrane system organization | IMP | biological_process |
GO:0015031 | Protein transport | IEA | biological_process |
GO:0016192 | Vesicle-mediated transport | IBA | biological_process |
GO:0016363 | Nuclear matrix | IEA | cellular_component |
GO:0017022 | Myosin binding | IPI | molecular_function |
GO:0030532 | Small nuclear ribonucleoprotein complex | IDA | cellular_component |
GO:0030837 | Negative regulation of actin filament polymerization | IMP | biological_process |
GO:0032012 | Regulation of ARF protein signal transduction | IEA | biological_process |
GO:0034237 | Protein kinase A regulatory subunit binding | IDA | molecular_function |
GO:0034259 | Negative regulation of Rho GTPase activity | IDA | biological_process |
GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
GO:0090284 | Positive regulation of protein glycosylation in Golgi | IMP | biological_process |
GO:0090303 | Positive regulation of wound healing | IMP | biological_process |
GO:2000114 | Regulation of establishment of cell polarity | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.0785812621 | 0.9169350329 | 0.5909999715 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Down | -0.0038052588 |
GSE13712_SHEAR | Up | 0.1984359166 |
GSE13712_STATIC | Up | 0.0775117630 |
GSE19018 | Up | 0.2538691866 |
GSE19899_A1 | Down | -0.0429903065 |
GSE19899_A2 | Up | 0.0456314579 |
PubMed_21979375_A1 | Up | 0.1575043935 |
PubMed_21979375_A2 | Up | 0.6623502570 |
GSE35957 | Up | 0.1795400684 |
GSE36640 | Up | 0.3052250558 |
GSE54402 | Down | -0.1144892330 |
GSE9593 | Up | 0.3042248386 |
GSE43922 | Down | -0.0309944815 |
GSE24585 | Up | 0.0597685445 |
GSE37065 | Up | 0.0736387505 |
GSE28863_A1 | Up | 0.7598569052 |
GSE28863_A2 | Up | 0.6267322251 |
GSE28863_A3 | Down | -0.5856079194 |
GSE28863_A4 | Up | 0.0612491788 |
GSE48662 | Up | 0.0873021532 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-215-5p | MIMAT0000272 | MIRT024514 | Microarray | Functional MTI (Weak) | 19074876 |
hsa-miR-192-5p | MIMAT0000222 | MIRT026910 | Microarray | Functional MTI (Weak) | 19074876 |
hsa-miR-877-3p | MIMAT0004950 | MIRT037025 | CLASH | Functional MTI (Weak) | 23622248 |
hsa-miR-125a-3p | MIMAT0004602 | MIRT038638 | CLASH | Functional MTI (Weak) | 23622248 |
hsa-miR-10b-5p | MIMAT0000254 | MIRT047437 | CLASH | Functional MTI (Weak) | 23622248 |
hsa-miR-10a-5p | MIMAT0000253 | MIRT047646 | CLASH | Functional MTI (Weak) | 23622248 |
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