HCSGD entry for CXCL13

1. General information

Official gene symbolCXCL13
Entrez ID10563
Gene full namechemokine (C-X-C motif) ligand 13
Other gene symbolsANGIE ANGIE2 BCA-1 BCA1 BLC BLR1L SCYB13
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002467Germinal center formationNASbiological_process
GO:0002518Lymphocyte chemotaxis across high endothelial venuleISSbiological_process
GO:0002544Chronic inflammatory responseNASbiological_process
GO:0002920Regulation of humoral immune responseNASbiological_process
GO:0005576Extracellular regionIDA TAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0006955Immune responseICbiological_process
GO:0007166Cell surface receptor signaling pathwayIDAbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationIDAbiological_process
GO:0007267Cell-cell signalingIDAbiological_process
GO:0008009Chemokine activityIDAmolecular_function
GO:0008201Heparin bindingIDAmolecular_function
GO:0010469Regulation of receptor activityIDAbiological_process
GO:0010820Positive regulation of T cell chemotaxisIDAbiological_process
GO:0017134Fibroblast growth factor bindingIDAmolecular_function
GO:0031724CXCR5 chemokine receptor bindingIDAmolecular_function
GO:0031735CCR10 chemokine receptor bindingIDAmolecular_function
GO:0032861Activation of Rap GTPase activityISSbiological_process
GO:0033625Positive regulation of integrin activationISSbiological_process
GO:0033634Positive regulation of cell-cell adhesion mediated by integrinISSbiological_process
GO:0035754B cell chemotaxisIDAbiological_process
GO:0035768Endothelial cell chemotaxis to fibroblast growth factorIDAbiological_process
GO:0035769B cell chemotaxis across high endothelial venuleIEAbiological_process
GO:0042742Defense response to bacteriumIDAbiological_process
GO:0045765Regulation of angiogenesisNASbiological_process
GO:0046982Protein heterodimerization activityIDAmolecular_function
GO:0048018Receptor agonist activityIDAmolecular_function
GO:0048248CXCR3 chemokine receptor bindingIPImolecular_function
GO:0048535Lymph node developmentIEAbiological_process
GO:2000273Positive regulation of receptor activityIDAbiological_process
GO:2000545Negative regulation of endothelial cell chemotaxis to fibroblast growth factorIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.32411702440.88129800160.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0818892555
GSE13712_SHEARDown-0.1421765346
GSE13712_STATICDown-0.1974299155
GSE19018Up0.1185295759
GSE19899_A1Up0.0610594910
GSE19899_A2Up0.1606223503
PubMed_21979375_A1Up0.0697256141
PubMed_21979375_A2Up0.1577988104
GSE35957Up0.1282428886
GSE36640Down-0.0016152897
GSE54402Up0.0309494271
GSE9593Up0.0670203335
GSE43922Up0.0192118406
GSE24585Up0.0823656897
GSE37065Up1.0804621056
GSE28863_A1Up0.0939732115
GSE28863_A2Up0.1038748862
GSE28863_A3Up0.0798745032
GSE28863_A4Up0.1253937530
GSE48662Up0.0276363893

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT028916MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.