HCSGD entry for CEL

1. General information

Official gene symbolCEL
Entrez ID1056
Gene full namecarboxyl ester lipase
Other gene symbolsBAL BSDL BSSL CELL CEase FAP FAPP LIPA MODY8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003824Catalytic activityTASmolecular_function
GO:0004771Sterol esterase activityNAS TASmolecular_function
GO:0004806Triglyceride lipase activityNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIBAcellular_component
GO:0005737CytoplasmISScellular_component
GO:0005829CytosolIBAcellular_component
GO:0006629Lipid metabolic processNASbiological_process
GO:0006641Triglyceride metabolic processICbiological_process
GO:0006707Cholesterol catabolic processIDA NASbiological_process
GO:0008201Heparin bindingNASmolecular_function
GO:0009062Fatty acid catabolic processNASbiological_process
GO:0016787Hydrolase activityTASmolecular_function
GO:0018350Protein esterificationNASbiological_process
GO:0030157Pancreatic juice secretionIDAbiological_process
GO:0030299Intestinal cholesterol absorptionNASbiological_process
GO:0044241Lipid digestionTASbiological_process
GO:0044258Intestinal lipid catabolic processNASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046514Ceramide catabolic processIEAbiological_process
GO:0047372Acylglycerol lipase activityTASmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15080536070.89726094750.77583509181.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1728117031
GSE13712_SHEARUp0.2692413034
GSE13712_STATICUp0.1176223577
GSE19018Up0.0527783700
GSE19899_A1Up0.0047515551
GSE19899_A2Down-0.0875347147
PubMed_21979375_A1Up1.6035032016
PubMed_21979375_A2Up0.2605531423
GSE35957Down-0.1070089101
GSE36640Up0.0893881338
GSE54402Down-0.2012520655
GSE9593Down-0.0770784342
GSE43922Up0.0146001632
GSE24585Up0.0872789114
GSE37065Down-0.0737565688
GSE28863_A1Up0.0387766268
GSE28863_A2Up0.5435022999
GSE28863_A3Up0.1497882445
GSE28863_A4Up0.2049396020
GSE48662Up0.0370673096

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017217MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.