HCSGD entry for RPP30


1. General information

Official gene symbolRPP30
Entrez ID10556
Gene full nameribonuclease P/MRP 30kDa subunit
Other gene symbolsTSG15
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004526Ribonuclease P activityIEAmolecular_function
GO:0004540Ribonuclease activityIEAmolecular_function
GO:0005634NucleusTAScellular_component
GO:0005655Nucleolar ribonuclease P complexTAScellular_component
GO:0008033TRNA processingIEAbiological_process
GO:0090305Nucleic acid phosphodiester bond hydrolysisTASbiological_process
GO:0090501RNA phosphodiester bond hydrolysisTASbiological_process
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolyticTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.18752021580.79739867030.84402224311.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3448603535
GSE13712_SHEARUp0.3029799031
GSE13712_STATICUp0.1642110530
GSE19018Down-0.0458767070
GSE19899_A1Up0.0276787938
GSE19899_A2Down-0.1398352095
PubMed_21979375_A1Up0.2932128706
PubMed_21979375_A2Up0.2918585667
GSE35957Down-0.2536473573
GSE36640Down-0.4142367174
GSE54402Up0.1134158370
GSE9593Up0.0971268115
GSE43922Up0.1428427369
GSE24585Down-0.2361827500
GSE37065Up0.0608743708
GSE28863_A1Up0.0379652639
GSE28863_A2Up0.4722571915
GSE28863_A3Down-0.5171043371
GSE28863_A4Up0.2635791553
GSE48662Up0.0401658822

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-615-3pMIMAT0003283MIRT039974CLASHFunctional MTI (Weak)23622248
hsa-miR-324-5pMIMAT0000761MIRT043167CLASHFunctional MTI (Weak)23622248
hsa-miR-106b-5pMIMAT0000680MIRT044349CLASHFunctional MTI (Weak)23622248
hsa-miR-15a-5pMIMAT0000068MIRT051319CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.