HCSGD entry for AGPAT1

1. General information

Official gene symbolAGPAT1
Entrez ID10554
Gene full name1-acylglycerol-3-phosphate O-acyltransferase 1
Other gene symbols1-AGPAT1 G15 LPAAT-alpha LPAATA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001819Positive regulation of cytokine productionIMPbiological_process
GO:0001961Positive regulation of cytokine-mediated signaling pathwayICbiological_process
GO:00038411-acylglycerol-3-phosphate O-acyltransferase activityIEA IGImolecular_function
GO:0005783Endoplasmic reticulumTAScellular_component
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0006644Phospholipid metabolic processTASbiological_process
GO:0006654Phosphatidic acid biosynthetic processIEA IGI TASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016024CDP-diacylglycerol biosynthetic processIEAbiological_process
GO:0019432Triglyceride biosynthetic processTASbiological_process
GO:0031325Positive regulation of cellular metabolic processTASbiological_process
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046474Glycerophospholipid biosynthetic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01860533030.97934310250.33377295641.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2716629184
GSE13712_SHEARDown-0.5661502135
GSE13712_STATICDown-0.1774871655
GSE19018Up0.2280797365
GSE19899_A1Up0.2210520079
GSE19899_A2Up0.4456407205
PubMed_21979375_A1Up1.2301907193
PubMed_21979375_A2Up2.0465551366
GSE35957Down-0.0031413630
GSE36640Up0.7005214475
GSE54402Up0.2211610624
GSE9593Down-0.1249827082
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.4061550951

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-193b-3pMIMAT0002819MIRT016494MicroarrayFunctional MTI (Weak)20304954
hsa-miR-7-5pMIMAT0000252MIRT025835MicroarrayFunctional MTI (Weak)19073608
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.