HCSGD entry for PRDX4
1. General information
| Official gene symbol | PRDX4 |
|---|---|
| Entrez ID | 10549 |
| Gene full name | peroxiredoxin 4 |
| Other gene symbols | AOE37-2 PRX-4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0007252 | I-kappaB phosphorylation | TAS | biological_process |
| GO:0007283 | Spermatogenesis | IEA | biological_process |
| GO:0008379 | Thioredoxin peroxidase activity | TAS | molecular_function |
| GO:0008584 | Male gonad development | IEA | biological_process |
| GO:0016209 | Antioxidant activity | IEA | molecular_function |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0051920 | Peroxiredoxin activity | IEA | molecular_function |
| GO:0072593 | Reactive oxygen species metabolic process | IEA | biological_process |
| GO:2000255 | Negative regulation of male germ cell proliferation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0791879526 | 0.6135238745 | 0.5923630861 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0619618572 |
| GSE13712_SHEAR | Up | 0.2422767812 |
| GSE13712_STATIC | Up | 0.0858523097 |
| GSE19018 | Up | 1.5863142194 |
| GSE19899_A1 | Up | 0.1999152773 |
| GSE19899_A2 | Up | 0.2717870300 |
| PubMed_21979375_A1 | Up | 0.9000447280 |
| PubMed_21979375_A2 | Up | 0.3673454430 |
| GSE35957 | Down | -0.2454515175 |
| GSE36640 | Up | 0.3843485843 |
| GSE54402 | Down | -0.3054692951 |
| GSE9593 | Up | 0.1399821378 |
| GSE43922 | Up | 0.1397923375 |
| GSE24585 | Down | -0.6004600556 |
| GSE37065 | Down | -0.2550236786 |
| GSE28863_A1 | Up | 0.0384917195 |
| GSE28863_A2 | Up | 0.0753041119 |
| GSE28863_A3 | Down | -0.3436994585 |
| GSE28863_A4 | Down | -0.0734245657 |
| GSE48662 | Down | -0.0744109912 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036386 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-769-5p | MIMAT0003886 | MIRT039210 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039796 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041872 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046583 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-3619-5p | MIMAT0017999 | MIRT052859 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
