HCSGD entry for RNASEH2A
1. General information
| Official gene symbol | RNASEH2A |
|---|---|
| Entrez ID | 10535 |
| Gene full name | ribonuclease H2, subunit A |
| Other gene symbols | AGS4 JUNB RNASEHI RNHIA RNHL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0004523 | RNA-DNA hybrid ribonuclease activity | IDA | molecular_function |
| GO:0004540 | Ribonuclease activity | TAS | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006260 | DNA replication | TAS | biological_process |
| GO:0006298 | Mismatch repair | IDA | biological_process |
| GO:0006401 | RNA catabolic process | IDA | biological_process |
| GO:0032299 | Ribonuclease H2 complex | IDA | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0090305 | Nucleic acid phosphodiester bond hydrolysis | IDA TAS | biological_process |
| GO:0090501 | RNA phosphodiester bond hydrolysis | IDA TAS | biological_process |
| GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic | IDA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9928570495 | 0.0000366171 | 0.9999902473 | 0.0107777778 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.9800469098 |
| GSE13712_SHEAR | Down | -0.8534376626 |
| GSE13712_STATIC | Down | -0.9739255080 |
| GSE19018 | Up | 0.1155975901 |
| GSE19899_A1 | Down | -1.8264228459 |
| GSE19899_A2 | Down | -4.2018426224 |
| PubMed_21979375_A1 | Down | -2.7767675769 |
| PubMed_21979375_A2 | Down | -5.2633098908 |
| GSE35957 | Down | -3.9433491528 |
| GSE36640 | Down | -3.7388689114 |
| GSE54402 | Down | -0.6697504864 |
| GSE9593 | Down | -1.3576839405 |
| GSE43922 | Down | -0.8648282518 |
| GSE24585 | Up | 0.1062697478 |
| GSE37065 | Down | -0.5073284987 |
| GSE28863_A1 | Down | -0.2335286283 |
| GSE28863_A2 | Up | 0.1551700553 |
| GSE28863_A3 | Up | 0.0900157079 |
| GSE28863_A4 | Up | 0.2410034799 |
| GSE48662 | Down | -0.8497274943 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046003 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050223 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
