HCSGD entry for IPO8
1. General information
| Official gene symbol | IPO8 |
|---|---|
| Entrez ID | 10526 |
| Gene full name | importin 8 |
| Other gene symbols | RANBP8 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008536 | Ran GTPase binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8711624216 | 0.0785753505 | 0.9999902473 | 0.5303030256 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1224114855 |
| GSE13712_SHEAR | Down | -0.5086405142 |
| GSE13712_STATIC | Down | -0.4089179824 |
| GSE19018 | Down | -0.0095468530 |
| GSE19899_A1 | Down | -0.2348819222 |
| GSE19899_A2 | Down | -0.7291277466 |
| PubMed_21979375_A1 | Down | -0.1316860852 |
| PubMed_21979375_A2 | Down | -0.1851747239 |
| GSE35957 | Up | 0.0507366480 |
| GSE36640 | Down | -0.3509362265 |
| GSE54402 | Down | -0.1661281393 |
| GSE9593 | Down | -0.1561134153 |
| GSE43922 | Down | -0.1925338450 |
| GSE24585 | Down | -0.1167573181 |
| GSE37065 | Up | 0.0438991084 |
| GSE28863_A1 | Up | 0.5613676522 |
| GSE28863_A2 | Up | 0.6155765481 |
| GSE28863_A3 | Down | -0.4645220414 |
| GSE28863_A4 | Up | 0.2128935001 |
| GSE48662 | Up | 0.1029425083 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020599 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023609 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032284 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041468 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
