HCSGD entry for CIB1

1. General information

Official gene symbolCIB1
Entrez ID10519
Gene full namecalcium and integrin binding 1 (calmyrin)
Other gene symbolsCIB CIBP KIP1 PRKDCIP SIP2-28
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001934Positive regulation of protein phosphorylationISSbiological_process
GO:0002931Response to ischemiaISSbiological_process
GO:0005509Calcium ion bindingIMPmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmIMPcellular_component
GO:0005737CytoplasmIDA IMPcellular_component
GO:0005783Endoplasmic reticulumIMPcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006302Double-strand break repairTASbiological_process
GO:0006915Apoptotic processIMPbiological_process
GO:0006974Cellular response to DNA damage stimulusIDAbiological_process
GO:0007026Negative regulation of microtubule depolymerizationIDAbiological_process
GO:0007113Endomitotic cell cycleIDAbiological_process
GO:0007155Cell adhesionTASbiological_process
GO:0007286Spermatid developmentISSbiological_process
GO:0008284Positive regulation of cell proliferationISSbiological_process
GO:0008285Negative regulation of cell proliferationIMPbiological_process
GO:0010977Negative regulation of neuron projection developmentIDAbiological_process
GO:0016020MembraneIDAcellular_component
GO:0016324Apical plasma membraneIEAcellular_component
GO:0017016Ras GTPase bindingIPImolecular_function
GO:0030027LamellipodiumIDAcellular_component
GO:0030175FilopodiumIEAcellular_component
GO:0030307Positive regulation of cell growthISSbiological_process
GO:0030426Growth coneIDAcellular_component
GO:0033630Positive regulation of cell adhesion mediated by integrinIDAbiological_process
GO:0042383SarcolemmaIDAcellular_component
GO:0043005Neuron projectionIDAcellular_component
GO:0043025Neuronal cell bodyIDAcellular_component
GO:0043066Negative regulation of apoptotic processIMP ISSbiological_process
GO:0043495Protein anchorIGImolecular_function
GO:0044325Ion channel bindingIEAmolecular_function
GO:0048471Perinuclear region of cytoplasmIDAcellular_component
GO:0048554Positive regulation of metalloenzyme activityISSbiological_process
GO:0051092Positive regulation of NF-kappaB transcription factor activityIMPbiological_process
GO:0051781Positive regulation of cell divisionISSbiological_process
GO:0070374Positive regulation of ERK1 and ERK2 cascadeISSbiological_process
GO:0070886Positive regulation of calcineurin-NFAT signaling cascadeIDAbiological_process
GO:0071356Cellular response to tumor necrosis factorIMPbiological_process
GO:0071363Cellular response to growth factor stimulusISSbiological_process
GO:0071902Positive regulation of protein serine/threonine kinase activityISSbiological_process
GO:0071944Cell peripheryIDAcellular_component
GO:0090004Positive regulation of establishment of protein localization to plasma membraneIGIbiological_process
GO:0090050Positive regulation of cell migration involved in sprouting angiogenesisISSbiological_process
GO:0090314Positive regulation of protein targeting to membraneIMPbiological_process
GO:0097191Extrinsic apoptotic signaling pathwayTASbiological_process
GO:1900026Positive regulation of substrate adhesion-dependent cell spreadingIDAbiological_process
GO:1901313Positive regulation of gene expression involved in extracellular matrix organizationISSbiological_process
GO:1990090Cellular response to nerve growth factor stimulusIDAbiological_process
GO:2000256Positive regulation of male germ cell proliferationISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03440327880.93291120020.42586497411.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.9364085987
GSE13712_SHEARUp0.0124274711
GSE13712_STATICUp0.3125156382
GSE19018Up0.5170619647
GSE19899_A1Up0.1695045541
GSE19899_A2Up0.4003779038
PubMed_21979375_A1Up0.3118940800
PubMed_21979375_A2Down-0.0145456356
GSE35957Down-0.3638872977
GSE36640Up0.0803533721
GSE54402Up0.7556553087
GSE9593Up0.1321985353
GSE43922Up0.1880488743
GSE24585Down-0.0010755609
GSE37065Up0.1556223543
GSE28863_A1Up0.0675899229
GSE28863_A2Down-0.0972437480
GSE28863_A3Down-0.3957064538
GSE28863_A4Up0.1381856696
GSE48662Down-0.1062043541

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029584MicroarrayFunctional MTI (Weak)19088304
hsa-miR-16-5pMIMAT0000069MIRT031749ProteomicsFunctional MTI (Weak)18668040
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.