HCSGD entry for STK25
1. General information
| Official gene symbol | STK25 |
|---|---|
| Entrez ID | 10494 |
| Gene full name | serine/threonine kinase 25 |
| Other gene symbols | SOK1 YSK1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | IEA TAS | molecular_function |
| GO:0004702 | Receptor signaling protein serine/threonine kinase activity | IBA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IBA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0006915 | Apoptotic process | IBA | biological_process |
| GO:0006979 | Response to oxidative stress | TAS | biological_process |
| GO:0007163 | Establishment or maintenance of cell polarity | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0023014 | Signal transduction by phosphorylation | IBA | biological_process |
| GO:0035556 | Intracellular signal transduction | IBA | biological_process |
| GO:0045595 | Regulation of cell differentiation | IBA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0050772 | Positive regulation of axonogenesis | IEA | biological_process |
| GO:0051645 | Golgi localization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3750765320 | 0.0805486342 | 0.9999902473 | 0.5366108833 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4408669711 |
| GSE13712_SHEAR | Up | 0.0867493554 |
| GSE13712_STATIC | Up | 0.1738977322 |
| GSE19018 | Up | 0.6985791907 |
| GSE19899_A1 | Down | -0.2541657930 |
| GSE19899_A2 | Up | 0.4562080953 |
| PubMed_21979375_A1 | Up | 0.7033062725 |
| PubMed_21979375_A2 | Up | 0.4567724189 |
| GSE35957 | Down | -0.1679244093 |
| GSE36640 | Up | 0.1711578003 |
| GSE54402 | Up | 0.3095924309 |
| GSE9593 | Down | -0.2479419385 |
| GSE43922 | Down | -0.0398933948 |
| GSE24585 | Down | -0.1482389503 |
| GSE37065 | Down | -0.4535609829 |
| GSE28863_A1 | Down | -0.3949327704 |
| GSE28863_A2 | Down | -0.1348822966 |
| GSE28863_A3 | Down | -0.2713581113 |
| GSE28863_A4 | Down | -0.5402136368 |
| GSE48662 | Up | 0.2449271256 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-186-5p | MIMAT0000456 | MIRT044928 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049469 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
