HCSGD entry for NXF1
1. General information
| Official gene symbol | NXF1 |
|---|---|
| Entrez ID | 10482 |
| Gene full name | nuclear RNA export factor 1 |
| Other gene symbols | MEX67 TAP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0000346 | Transcription export complex | IDA | cellular_component |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0003729 | MRNA binding | IEA | molecular_function |
| GO:0005487 | Nucleocytoplasmic transporter activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005643 | Nuclear pore | IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006406 | MRNA export from nucleus | IDA IEA TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0016607 | Nuclear speck | IDA | cellular_component |
| GO:0016973 | Poly(A)+ mRNA export from nucleus | IEA | biological_process |
| GO:0042405 | Nuclear inclusion body | IEA | cellular_component |
| GO:0051028 | MRNA transport | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2939244824 | 0.2559077429 | 0.9939905447 | 0.9701494599 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1983645576 |
| GSE13712_SHEAR | Down | -0.3496064010 |
| GSE13712_STATIC | Down | -0.3123460439 |
| GSE19018 | Down | -0.8408406188 |
| GSE19899_A1 | Down | -0.1830174381 |
| GSE19899_A2 | Up | 0.0185672026 |
| PubMed_21979375_A1 | Up | 0.1637648022 |
| PubMed_21979375_A2 | Up | 0.0651316118 |
| GSE35957 | Down | -0.3268634189 |
| GSE36640 | Up | 0.2919672465 |
| GSE54402 | Up | 0.3803360337 |
| GSE9593 | Down | -0.3944556543 |
| GSE43922 | Up | 0.0369913710 |
| GSE24585 | Up | 0.7524562319 |
| GSE37065 | Up | 0.0859659370 |
| GSE28863_A1 | Up | 0.3762230882 |
| GSE28863_A2 | Up | 0.3872946247 |
| GSE28863_A3 | Down | -0.3096871566 |
| GSE28863_A4 | Down | -0.0473985245 |
| GSE48662 | Down | -0.1438762513 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT039654 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
