HCSGD entry for UBE2E3
1. General information
| Official gene symbol | UBE2E3 |
|---|---|
| Entrez ID | 10477 |
| Gene full name | ubiquitin-conjugating enzyme E2E 3 |
| Other gene symbols | UBCH9 UbcM2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0016881 | Acid-amino acid ligase activity | IEA | molecular_function |
| GO:0040008 | Regulation of growth | IEA | biological_process |
| GO:0070534 | Protein K63-linked ubiquitination | IDA | biological_process |
| GO:0070936 | Protein K48-linked ubiquitination | IDA | biological_process |
| GO:0070979 | Protein K11-linked ubiquitination | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6579374644 | 0.4967580069 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2482524894 |
| GSE13712_SHEAR | Down | -0.2562617098 |
| GSE13712_STATIC | Down | -0.0075316230 |
| GSE19018 | Down | -0.0409664660 |
| GSE19899_A1 | Up | 0.2434161058 |
| GSE19899_A2 | Down | -0.0168533344 |
| PubMed_21979375_A1 | Up | 0.3427693781 |
| PubMed_21979375_A2 | Up | 0.2106919293 |
| GSE35957 | Down | -0.2663383253 |
| GSE36640 | Down | -0.4660356461 |
| GSE54402 | Up | 0.1593395428 |
| GSE9593 | Down | -0.2646892500 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.1778356983 |
| GSE28863_A2 | Down | -0.0149991254 |
| GSE28863_A3 | Down | -0.2435219603 |
| GSE28863_A4 | Up | 0.1388110906 |
| GSE48662 | Down | -0.4190429625 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-186-5p | MIMAT0000456 | MIRT045204 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048393 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
