HCSGD entry for ZBTB18
1. General information
| Official gene symbol | ZBTB18 |
|---|---|
| Entrez ID | 10472 |
| Gene full name | zinc finger and BTB domain containing 18 |
| Other gene symbols | C2H2-171 RP58 TAZ-1 ZNF238 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | ISS | biological_process |
| GO:0000228 | Nuclear chromosome | TAS | cellular_component |
| GO:0001701 | In utero embryonic development | IEA | biological_process |
| GO:0003677 | DNA binding | TAS | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | TAS | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007519 | Skeletal muscle tissue development | ISS | biological_process |
| GO:0021549 | Cerebellum development | IEA | biological_process |
| GO:0021766 | Hippocampus development | IEA | biological_process |
| GO:0021987 | Cerebral cortex development | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IDA | molecular_function |
| GO:0045892 | Negative regulation of transcription, DNA-templated | ISS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048666 | Neuron development | IEA | biological_process |
| GO:0048872 | Homeostasis of number of cells | IEA | biological_process |
| GO:0051302 | Regulation of cell division | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9860450705 | 0.0112989856 | 0.9999902473 | 0.2101771025 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5813566877 |
| GSE13712_SHEAR | Up | 0.2996393929 |
| GSE13712_STATIC | Down | -0.0410051415 |
| GSE19018 | Up | 0.0680034724 |
| GSE19899_A1 | Down | -0.6716458140 |
| GSE19899_A2 | Down | -0.9588751202 |
| PubMed_21979375_A1 | Down | -1.6888876218 |
| PubMed_21979375_A2 | Down | -0.8777677962 |
| GSE35957 | Down | -0.2905157498 |
| GSE36640 | Down | -0.2842461155 |
| GSE54402 | Down | -0.8508493293 |
| GSE9593 | Up | 0.0072313644 |
| GSE43922 | Down | -0.4376085012 |
| GSE24585 | Down | -0.2475281932 |
| GSE37065 | Up | 0.0477259622 |
| GSE28863_A1 | Up | 0.1144642312 |
| GSE28863_A2 | Up | 0.0013009362 |
| GSE28863_A3 | Up | 0.0096028931 |
| GSE28863_A4 | Down | -0.0489944880 |
| GSE48662 | Down | -0.1966191734 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-338-3p | MIMAT0000763 | MIRT003042 | qRT-PCR//Western blot | Functional MTI | 18684991 |
| hsa-miR-590-3p | MIMAT0004801 | MIRT016212 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-548b-3p | MIMAT0003254 | MIRT016240 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT021920 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024510 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026265 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029041 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029041 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036898 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-3p | MIMAT0004672 | MIRT038588 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
