HCSGD entry for ECI2
1. General information
| Official gene symbol | ECI2 |
|---|---|
| Entrez ID | 10455 |
| Gene full name | enoyl-CoA delta isomerase 2 |
| Other gene symbols | ACBD2 DRS-1 DRS1 HCA88 PECI dJ1013A10.3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000062 | Fatty-acyl-CoA binding | IEA | molecular_function |
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0004165 | Dodecenoyl-CoA delta-isomerase activity | IDA IEA | molecular_function |
| GO:0005102 | Receptor binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005782 | Peroxisomal matrix | IDA IEA | cellular_component |
| GO:0009062 | Fatty acid catabolic process | IDA | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9298029596 | 0.0182021352 | 0.9999902473 | 0.2639560022 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3109595480 |
| GSE13712_SHEAR | Up | 0.0836438020 |
| GSE13712_STATIC | Up | 0.4926107046 |
| GSE19018 | Up | 0.2955154594 |
| GSE19899_A1 | Down | -0.8419543072 |
| GSE19899_A2 | Down | -0.9400280698 |
| PubMed_21979375_A1 | Down | -0.6504267993 |
| PubMed_21979375_A2 | Down | -0.9253516672 |
| GSE35957 | Down | -0.5719641216 |
| GSE36640 | Down | -0.2252976855 |
| GSE54402 | Down | -0.0402057769 |
| GSE9593 | Down | -0.1611405722 |
| GSE43922 | Down | -0.3621555385 |
| GSE24585 | Down | -0.2596602911 |
| GSE37065 | Down | -0.0354259157 |
| GSE28863_A1 | Up | 0.0100475035 |
| GSE28863_A2 | Up | 0.0476780009 |
| GSE28863_A3 | Down | -0.6946288446 |
| GSE28863_A4 | Down | -0.0946876674 |
| GSE48662 | Down | -0.5235975535 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| MYRISTIC ACID | DB08231 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT005655 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT005655 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030944 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036886 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
