HCSGD entry for TOMM40
1. General information
| Official gene symbol | TOMM40 |
|---|---|
| Entrez ID | 10452 |
| Gene full name | translocase of outer mitochondrial membrane 40 homolog (yeast) |
| Other gene symbols | C19orf1 D19S1177E PER-EC1 PEREC1 TOM40 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005739 | Mitochondrion | IMP | cellular_component |
| GO:0005741 | Mitochondrial outer membrane | IEA | cellular_component |
| GO:0005742 | Mitochondrial outer membrane translocase complex | IDA | cellular_component |
| GO:0006626 | Protein targeting to mitochondrion | IMP TAS | biological_process |
| GO:0006811 | Ion transport | IEA | biological_process |
| GO:0008320 | Protein transmembrane transporter activity | ISS TAS | molecular_function |
| GO:0015288 | Porin activity | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IDA | cellular_component |
| GO:0031307 | Integral component of mitochondrial outer membrane | ISS | cellular_component |
| GO:0032592 | Integral component of mitochondrial membrane | IEA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0046930 | Pore complex | IEA | cellular_component |
| GO:0055085 | Transmembrane transport | IEA | biological_process |
| GO:0071806 | Protein transmembrane transport | ISS TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3920909616 | 0.0682160176 | 0.9999902473 | 0.4929056272 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3304758981 |
| GSE13712_SHEAR | Down | -0.1625141208 |
| GSE13712_STATIC | Up | 0.1644156118 |
| GSE19018 | Down | -0.4931522684 |
| GSE19899_A1 | Down | -0.3193486448 |
| GSE19899_A2 | Up | 0.3990602235 |
| PubMed_21979375_A1 | Up | 0.0689179626 |
| PubMed_21979375_A2 | Up | 0.1147825500 |
| GSE35957 | Down | -0.7439622181 |
| GSE36640 | Down | -0.8777889619 |
| GSE54402 | Up | 0.7350791260 |
| GSE9593 | Down | -0.8146458574 |
| GSE43922 | Up | 0.2399374290 |
| GSE24585 | Down | -0.8379479321 |
| GSE37065 | Down | -0.2134570012 |
| GSE28863_A1 | Down | -0.0983382804 |
| GSE28863_A2 | Down | -0.1440167645 |
| GSE28863_A3 | Up | 0.1991788297 |
| GSE28863_A4 | Up | 0.1000172273 |
| GSE48662 | Up | 0.0349437196 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025243 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040094 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042204 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042816 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
