HCSGD entry for PPIE
1. General information
| Official gene symbol | PPIE |
|---|---|
| Entrez ID | 10450 |
| Gene full name | peptidylprolyl isomerase E (cyclophilin E) |
| Other gene symbols | CYP-33 CYP33 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0000398 | MRNA splicing, via spliceosome | IC | biological_process |
| GO:0000413 | Protein peptidyl-prolyl isomerization | TAS | biological_process |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003723 | RNA binding | TAS | molecular_function |
| GO:0003755 | Peptidyl-prolyl cis-trans isomerase activity | IEA TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006355 | Regulation of transcription, DNA-templated | IMP | biological_process |
| GO:0006457 | Protein folding | IEA | biological_process |
| GO:0016018 | Cyclosporin A binding | TAS | molecular_function |
| GO:0045070 | Positive regulation of viral genome replication | IMP | biological_process |
| GO:0071013 | Catalytic step 2 spliceosome | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5452732913 | 0.7346050492 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1957250506 |
| GSE13712_SHEAR | Up | 0.0033643580 |
| GSE13712_STATIC | Up | 0.1114136584 |
| GSE19018 | Up | 0.1866724788 |
| GSE19899_A1 | Down | -0.0452515919 |
| GSE19899_A2 | Down | -0.1319005126 |
| PubMed_21979375_A1 | Up | 0.5971266253 |
| PubMed_21979375_A2 | Down | -0.4363175756 |
| GSE35957 | Down | -0.0664902250 |
| GSE36640 | Down | -0.3519229429 |
| GSE54402 | Up | 0.0688734619 |
| GSE9593 | Down | -0.3172383003 |
| GSE43922 | Up | 0.0566025110 |
| GSE24585 | Down | -0.1031508836 |
| GSE37065 | Up | 0.0106138374 |
| GSE28863_A1 | Up | 0.1582598948 |
| GSE28863_A2 | Up | 0.0100818570 |
| GSE28863_A3 | Up | 0.1552739145 |
| GSE28863_A4 | Up | 0.1305309397 |
| GSE48662 | Up | 0.1169688136 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-766-3p | MIMAT0003888 | MIRT039021 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042995 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-342-3p | MIMAT0000753 | MIRT043678 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
