HCSGD entry for ACAA2
1. General information
| Official gene symbol | ACAA2 |
|---|---|
| Entrez ID | 10449 |
| Gene full name | acetyl-CoA acyltransferase 2 |
| Other gene symbols | DSAEC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003988 | Acetyl-CoA C-acyltransferase activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IDA NAS | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0006631 | Fatty acid metabolic process | IEA | biological_process |
| GO:0006695 | Cholesterol biosynthetic process | NAS | biological_process |
| GO:0016747 | Transferase activity, transferring acyl groups other than amino-acyl groups | IEA | molecular_function |
| GO:1901029 | Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9922749972 | 0.0115013183 | 0.9999902473 | 0.2125289510 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0950961233 |
| GSE13712_SHEAR | Down | -0.1744399019 |
| GSE13712_STATIC | Down | -0.1452962314 |
| GSE19018 | Down | -0.4935978525 |
| GSE19899_A1 | Down | -0.4783324703 |
| GSE19899_A2 | Down | -0.7381599249 |
| PubMed_21979375_A1 | Down | -0.7356547563 |
| PubMed_21979375_A2 | Down | -0.7182136569 |
| GSE35957 | Up | 0.0467762056 |
| GSE36640 | Down | -0.2900145048 |
| GSE54402 | Down | -0.4692762428 |
| GSE9593 | Down | -0.1457374350 |
| GSE43922 | Down | -0.8019970376 |
| GSE24585 | Down | -0.1826575237 |
| GSE37065 | Down | -0.0035993204 |
| GSE28863_A1 | Up | 0.1892417056 |
| GSE28863_A2 | Down | -0.1790850191 |
| GSE28863_A3 | Down | -0.1115270669 |
| GSE28863_A4 | Down | -0.0286157012 |
| GSE48662 | Down | -0.2155081209 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002662 | Microarray//qRT-PCR | Functional MTI (Weak) | 16549876 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002662 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002662 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029760 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045050 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
