HCSGD entry for ARIH2
1. General information
| Official gene symbol | ARIH2 |
|---|---|
| Entrez ID | 10425 |
| Gene full name | ariadne homolog 2 (Drosophila) |
| Other gene symbols | ARI2 TRIAD1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000209 | Protein polyubiquitination | IDA | biological_process |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | IEA | biological_process |
| GO:0007275 | Multicellular organismal development | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0042787 | Protein ubiquitination involved in ubiquitin-dependent protein catabolic process | IDA | biological_process |
| GO:0048588 | Developmental cell growth | IDA | biological_process |
| GO:0070534 | Protein K63-linked ubiquitination | IDA | biological_process |
| GO:0070936 | Protein K48-linked ubiquitination | IDA | biological_process |
| GO:0071425 | Hematopoietic stem cell proliferation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3326668136 | 0.7094466434 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3427481509 |
| GSE13712_SHEAR | Up | 0.2862643359 |
| GSE13712_STATIC | Up | 0.1517160651 |
| GSE19018 | Down | -0.5004996790 |
| GSE19899_A1 | Up | 0.0053426894 |
| GSE19899_A2 | Up | 0.1676381442 |
| PubMed_21979375_A1 | Up | 0.6478885355 |
| PubMed_21979375_A2 | Up | 0.2751771987 |
| GSE35957 | Down | -0.3073397661 |
| GSE36640 | Down | -0.4384656391 |
| GSE54402 | Up | 0.3788559561 |
| GSE9593 | Down | -0.2332768264 |
| GSE43922 | Up | 0.0725143959 |
| GSE24585 | Up | 0.0318525456 |
| GSE37065 | Down | -0.0931919806 |
| GSE28863_A1 | Up | 0.0798685947 |
| GSE28863_A2 | Up | 0.0553698237 |
| GSE28863_A3 | Down | -0.1494894732 |
| GSE28863_A4 | Down | -0.0388273057 |
| GSE48662 | Up | 0.2042395437 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-221-3p | MIMAT0000278 | MIRT003366 | Reporter assay;Microarray | Non-Functional MTI | 20018759 |
| hsa-miR-19a-3p | MIMAT0000073 | MIRT005396 | qRT-PCR | Functional MTI (Weak) | 19296935 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028030 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-1301-3p | MIMAT0005797 | MIRT035998 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-342-3p | MIMAT0000753 | MIRT043669 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
