HCSGD entry for CD2BP2
1. General information
| Official gene symbol | CD2BP2 |
|---|---|
| Entrez ID | 10421 |
| Gene full name | CD2 (cytoplasmic tail) binding protein 2 |
| Other gene symbols | FWP010 LIN1 PPP1R59 Snu40 U5-52K |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000244 | Spliceosomal tri-snRNP complex assembly | NAS | biological_process |
| GO:0000398 | MRNA splicing, via spliceosome | TAS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | IDA TAS | cellular_component |
| GO:0005682 | U5 snRNP | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0010923 | Negative regulation of phosphatase activity | IDA | biological_process |
| GO:0016607 | Nuclear speck | IDA | cellular_component |
| GO:0043021 | Ribonucleoprotein complex binding | IDA | molecular_function |
| GO:0046540 | U4/U6 x U5 tri-snRNP complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1652659435 | 0.8543526424 | 0.8036144282 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3287806712 |
| GSE13712_SHEAR | Up | 0.2705831050 |
| GSE13712_STATIC | Down | -0.0374731646 |
| GSE19018 | Down | -0.3537575325 |
| GSE19899_A1 | Down | -0.0680440413 |
| GSE19899_A2 | Up | 0.4103784838 |
| PubMed_21979375_A1 | Up | 0.2483912399 |
| PubMed_21979375_A2 | Up | 0.2899879946 |
| GSE35957 | Down | -0.2418975136 |
| GSE36640 | Down | -0.2105902732 |
| GSE54402 | Up | 0.2990453136 |
| GSE9593 | Up | 0.0387883809 |
| GSE43922 | Up | 0.0441572456 |
| GSE24585 | Down | -0.3180883443 |
| GSE37065 | Down | -0.1668705568 |
| GSE28863_A1 | Up | 0.3628684543 |
| GSE28863_A2 | Up | 0.0831092030 |
| GSE28863_A3 | Up | 0.3157014595 |
| GSE28863_A4 | Up | 0.1772530782 |
| GSE48662 | Up | 0.1267949151 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022522 | Proteomics;Microarray | Non-Functional MTI (Weak) | 18668037 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039811 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042172 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049524 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051962 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-3679-3p | MIMAT0018105 | MIRT052875 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
