HCSGD entry for NDC80

1. General information

Official gene symbolNDC80
Entrez ID10403
Gene full nameNDC80 kinetochore complex component
Other gene symbolsHEC HEC1 HsHec1 KNTC2 TID3 hsNDC80
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000070Mitotic sister chromatid segregationTASbiological_process
GO:0000132Establishment of mitotic spindle orientationIMPbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0000775Chromosome, centromeric regionTAScellular_component
GO:0000776KinetochoreIDAcellular_component
GO:0000777Condensed chromosome kinetochoreIDAcellular_component
GO:0000942Condensed nuclear chromosome outer kinetochoreIDAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0007049Cell cycleNASbiological_process
GO:0007051Spindle organizationNASbiological_process
GO:0007052Mitotic spindle organizationIMPbiological_process
GO:0007059Chromosome segregationIMPbiological_process
GO:0007067MitosisTASbiological_process
GO:0008608Attachment of spindle microtubules to kinetochoreIMPbiological_process
GO:0031262Ndc80 complexIDAcellular_component
GO:0048015Phosphatidylinositol-mediated signalingNASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.92289304360.00000598000.99999024730.0069833333

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-2.3082449350
GSE13712_SHEARDown-0.2496051944
GSE13712_STATICDown-0.6530499705
GSE19018Down-0.0998063897
GSE19899_A1Down-2.2471860652
GSE19899_A2Down-4.7387762103
PubMed_21979375_A1Down-6.2225028389
PubMed_21979375_A2Down-7.2472197330
GSE35957Down-5.6277697800
GSE36640Down-5.0250238187
GSE54402Down-1.6152381005
GSE9593Down-2.5365404572
GSE43922Down-2.9856596582
GSE24585Down-0.0935614095
GSE37065Down-0.5123886121
GSE28863_A1Down-0.2996975973
GSE28863_A2Up1.2532695551
GSE28863_A3Down-0.4031694786
GSE28863_A4Up0.5607168104
GSE48662Down-2.0561693749

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-193b-3pMIMAT0002819MIRT016353MicroarrayFunctional MTI (Weak)20304954
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.