HCSGD entry for ADARB1
1. General information
| Official gene symbol | ADARB1 |
|---|---|
| Entrez ID | 104 |
| Gene full name | adenosine deaminase, RNA-specific, B1 |
| Other gene symbols | ADAR2 DRABA2 DRADA2 RED1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003723 | RNA binding | IDA IEA | molecular_function |
| GO:0003725 | Double-stranded RNA binding | IDA | molecular_function |
| GO:0003726 | Double-stranded RNA adenosine deaminase activity | IDA | molecular_function |
| GO:0003729 | MRNA binding | TAS | molecular_function |
| GO:0004000 | Adenosine deaminase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006382 | Adenosine to inosine editing | IDA IEA TAS | biological_process |
| GO:0006396 | RNA processing | IDA IEA | biological_process |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0008285 | Negative regulation of cell proliferation | IDA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016553 | Base conversion or substitution editing | IC | biological_process |
| GO:0016556 | MRNA modification | TAS | biological_process |
| GO:0030336 | Negative regulation of cell migration | IDA | biological_process |
| GO:0044387 | Negative regulation of protein kinase activity by regulation of protein phosphorylation | IDA | biological_process |
| GO:0045070 | Positive regulation of viral genome replication | IMP | biological_process |
| GO:0045087 | Innate immune response | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051607 | Defense response to virus | IEA | biological_process |
| GO:0051726 | Regulation of cell cycle | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9420959158 | 0.0074676646 | 0.9999902473 | 0.1729640598 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3904180526 |
| GSE13712_SHEAR | Down | -0.1366538927 |
| GSE13712_STATIC | Down | -0.0020357549 |
| GSE19018 | Down | -0.0419824702 |
| GSE19899_A1 | Down | -0.4616724912 |
| GSE19899_A2 | Down | -0.4182905631 |
| PubMed_21979375_A1 | Down | -0.8018501924 |
| PubMed_21979375_A2 | Down | -0.8181759659 |
| GSE35957 | Up | 0.2732611027 |
| GSE36640 | Down | -2.3295037766 |
| GSE54402 | Down | -0.9253144273 |
| GSE9593 | Down | -0.3703328328 |
| GSE43922 | Down | -0.2108242069 |
| GSE24585 | Down | -0.0277914593 |
| GSE37065 | Down | -0.0930702005 |
| GSE28863_A1 | Up | 0.8730175502 |
| GSE28863_A2 | Up | 0.0939186520 |
| GSE28863_A3 | Down | -0.9269327511 |
| GSE28863_A4 | Up | 0.0067113998 |
| GSE48662 | Up | 0.2358541914 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020174 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022259 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025443 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-148a-3p | MIMAT0000243 | MIRT025977 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT027945 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029036 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041526 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050812 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
