HCSGD entry for ATP8A1
1. General information
| Official gene symbol | ATP8A1 |
|---|---|
| Entrez ID | 10396 |
| Gene full name | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 |
| Other gene symbols | ATPASEII ATPIA ATPP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IEA | molecular_function |
| GO:0004012 | Phospholipid-translocating ATPase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006200 | ATP catabolic process | NAS | biological_process |
| GO:0008152 | Metabolic process | NAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019829 | Cation-transporting ATPase activity | IEA NAS | molecular_function |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0042584 | Chromaffin granule membrane | IEA | cellular_component |
| GO:0045332 | Phospholipid translocation | NAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1729842445 | 0.8071812089 | 0.8169959268 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1153767583 |
| GSE13712_SHEAR | Down | -0.8184202825 |
| GSE13712_STATIC | Down | -0.2016055951 |
| GSE19018 | Up | 0.0712620920 |
| GSE19899_A1 | Up | 0.0435845070 |
| GSE19899_A2 | Up | 0.2947087462 |
| PubMed_21979375_A1 | Up | 0.3770993619 |
| PubMed_21979375_A2 | Up | 0.2945166727 |
| GSE35957 | Up | 0.1231873781 |
| GSE36640 | Up | 0.5888841926 |
| GSE54402 | Up | 0.5118718511 |
| GSE9593 | Down | -0.0815434237 |
| GSE43922 | Up | 0.5778482713 |
| GSE24585 | Up | 0.2481672618 |
| GSE37065 | Up | 0.1576567663 |
| GSE28863_A1 | Down | -0.1094439454 |
| GSE28863_A2 | Down | -0.2022150695 |
| GSE28863_A3 | Down | -0.0219066633 |
| GSE28863_A4 | Up | 0.0113189068 |
| GSE48662 | Down | -0.2653088615 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Phosphatidyl serine | DB00144 | NUTR00048 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018577 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT022068 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025194 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
