HCSGD entry for IRF9

1. General information

Official gene symbolIRF9
Entrez ID10379
Gene full nameinterferon regulatory factor 9
Other gene symbolsIRF-9 ISGF3 ISGF3G p48
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000975Regulatory region DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusTAScellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0007166Cell surface receptor signaling pathwayTASbiological_process
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0045351Type I interferon biosynthetic processIEAbiological_process
GO:0051607Defense response to virusIEAbiological_process
GO:0060333Interferon-gamma-mediated signaling pathwayTASbiological_process
GO:0060337Type I interferon signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03141281490.11265340980.40998093120.6430085863

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3324241447
GSE13712_SHEARUp0.6805681669
GSE13712_STATICUp0.4148512542
GSE19018Down-0.2324796752
GSE19899_A1Down-0.4032283322
GSE19899_A2Down-1.3206154864
PubMed_21979375_A1Down-0.4469236358
PubMed_21979375_A2Down-0.1233171236
GSE35957Down-1.7204750189
GSE36640Up1.5117448929
GSE54402Up0.1738318618
GSE9593Up0.5546693314
GSE43922Down-0.4800934348
GSE24585Up2.1161901839
GSE37065Up0.5303490672
GSE28863_A1Down-0.0360137594
GSE28863_A2Up0.6594793751
GSE28863_A3Down-0.5959180594
GSE28863_A4Down-0.0664274512
GSE48662Down-0.1034207176

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-106b-5pMIMAT0000680MIRT020418MicroarrayFunctional MTI (Weak)17242205
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.