HCSGD entry for MICU1
1. General information
| Official gene symbol | MICU1 |
|---|---|
| Entrez ID | 10367 |
| Gene full name | mitochondrial calcium uptake 1 |
| Other gene symbols | CALC CBARA1 EFHA3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005509 | Calcium ion binding | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | TAS | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IDA | cellular_component |
| GO:0005758 | Mitochondrial intermembrane space | IDA | cellular_component |
| GO:0006851 | Mitochondrial calcium ion transport | IMP | biological_process |
| GO:0006952 | Defense response | TAS | biological_process |
| GO:0032592 | Integral component of mitochondrial membrane | IDA | cellular_component |
| GO:0034704 | Calcium channel complex | ISS | cellular_component |
| GO:0051560 | Mitochondrial calcium ion homeostasis | IMP | biological_process |
| GO:0070509 | Calcium ion import | IDA | biological_process |
| GO:1990246 | Uniplex complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0682950002 | 0.8279647468 | 0.5612215735 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0915424735 |
| GSE13712_SHEAR | Down | -0.3154663166 |
| GSE13712_STATIC | Down | -0.1928703399 |
| GSE19018 | Up | 0.3130740058 |
| GSE19899_A1 | Up | 0.1543172140 |
| GSE19899_A2 | Up | 0.7734049293 |
| PubMed_21979375_A1 | Up | 0.5842338051 |
| PubMed_21979375_A2 | Up | 1.0840339314 |
| GSE35957 | Down | -0.0049467658 |
| GSE36640 | Up | 0.8833198163 |
| GSE54402 | Down | -0.0234055113 |
| GSE9593 | Up | 0.2050691778 |
| GSE43922 | Down | -0.0360063234 |
| GSE24585 | Up | 0.2060189159 |
| GSE37065 | Down | -0.0343986273 |
| GSE28863_A1 | Up | 0.0654827745 |
| GSE28863_A2 | Up | 0.1835913464 |
| GSE28863_A3 | Down | -0.6462839593 |
| GSE28863_A4 | Down | -0.0601553165 |
| GSE48662 | Up | 0.3163844825 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-877-5p | MIMAT0004949 | MIRT037375 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
