HCSGD entry for WARS2
1. General information
| Official gene symbol | WARS2 |
|---|---|
| Entrez ID | 10352 |
| Gene full name | tryptophanyl tRNA synthetase 2, mitochondrial |
| Other gene symbols | TrpRS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001570 | Vasculogenesis | IEA | biological_process |
| GO:0004830 | Tryptophan-tRNA ligase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006418 | TRNA aminoacylation for protein translation | TAS | biological_process |
| GO:0006436 | Tryptophanyl-tRNA aminoacylation | IEA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8975355344 | 0.2052111204 | 0.9999902473 | 0.8786988612 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0551869106 |
| GSE13712_SHEAR | Down | -0.5309739626 |
| GSE13712_STATIC | Down | -0.4220262470 |
| GSE19018 | Up | 0.0381423472 |
| GSE19899_A1 | Up | 0.0350778666 |
| GSE19899_A2 | Up | 0.3637833923 |
| PubMed_21979375_A1 | Up | 0.4011236025 |
| PubMed_21979375_A2 | Up | 0.2098855313 |
| GSE35957 | Up | 0.1293413067 |
| GSE36640 | Down | -0.2720610226 |
| GSE54402 | Up | 0.1180603596 |
| GSE9593 | Down | -0.0389567151 |
| GSE43922 | Down | -0.2843749521 |
| GSE24585 | Down | -0.4797928089 |
| GSE37065 | Down | -0.2074811220 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.0231999893 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027840 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032492 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
